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  • Just Other Articles - Changing Careers? How to Get Around the Three Major Mental Roadblocks to Success

    A part of you can't wait to dive into your new career -- but you're also smart enough to know that you can expect a few bumps along the road to success. By far, the biggest roadblocks exist between your own two ears!


    Let's take a look at thre
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    e common mental roadblocks and learn how to overcome them.

    ROADBLOCK No. 1: Wishful Thinking



    How many times have you wished you'd hit the lottery? Now, how many times have you actually won the lottery? Far too many people spend far t
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    oo much time wishing when they should be dreaming.


    So, what's the difference between wishing and dreaming?


    Wishing is passive. We wish for things over which we have little or no control. We wish we were taller or thinner. We wish the waiter
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    would hurry up. We wish our boss wasn't so [you fill in the blank].


    The other thing about wishes is that they are often tinged with regrets about past decisions -- both big and small. We wish we'd ordered the fish instead of the chicken. We wi
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    sh we'd taken the other job. We wish we hadn't let the love of our life get away.


    Dreaming is different. For one, a dream is active. Unlike wishes, we can actually do something about a dream. After all, you don't "wish up" a plan, you dream on
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    up!


    You may not get everything you dream of getting, but two things are certain:


    1. It doesn't take a single extra ounce of energy to dream big than it does to settle.


    2. You've got a lot more to gain by shooting high than by shooting l
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ow.

    ROADBLOCK No. 2: What If Everyone Thinks You're Crazy?



    You've probably already thought about the people you can count on to support your plan to create a more meaningful work/life. But have you also taken stock of those you shoul
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    make a point NOT to turn to?


    Unless you come either from money or from a long line of pioneers, you may not get the support you want from your family. With the best of intentions, you may find your dream of quitting your job to pursue your dr
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    eam career met with advice to "play it safe," reminders that "you're lucky to have a good job," or a lecture on the seemingly insurmountable odds standing between you and success.


    No matter how old you are, or how much you deny it, family appr
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    val does matter. Which, of course, makes it all the more painful when the people we love fail to give us the emotional green light we so desperately seek.


    Other people's fear, skepticism, and negativity can be as contagious as the flu. And unl
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ess you've built up your immune system, these dream stompers can knock you for a loop -- especially when they are right in your own family.


    You have two choices. You can either continue to turn to these naysayers in hopes that they'll respond
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    differently -- or, you can choose the saner path of acceptance.


    Don't look for support from people whose life experiences have not prepared them to give it fully. Instead, take advantage of the support that really is available.

    ROADBLOCK

    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    No. 3: Fear of Change

    The closer you come to leaving the security of your 9-to-5 job (no matter how much you want out) the greater your level of excitement and trepidation (see "Word to the Wise," below).


    Anyone who has ever ventured o
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ut of their safe little world will tell you they had doubts. But when it comes to making a major life change, not only is a certain amount of fear perfectly normal, it's actually helpful. For example, it's our healthy fears that keep us from jump
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ng off cliffs. And the great thing about fear is that there are ways to get around it.


    So, try laughing in the face of fear. Am I kidding? No. Ridiculing your fears is actually a very effective technique for banishing them -- because the mind
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    rejects that which it considers absurd.


    The trick is to turn your fears into a ridiculous event in your mind. That way, you allow your natural human reaction to absurdity to take over and dismiss them.


    Try it yourself. Take your biggest fea
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    and take it to extremes. Really exaggerate it. Let's say you're paralyzed by the fear of failure. Try picturing your entire family, all of your friends, your neighbors, everyone you went to high school with, even your boss, standing outside your
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    cardboard-box home holding up signs that read: "We Told You So!"


    Pretty ridiculous, right? When you realize that your worst-case fantasy is just that -- a fantasy -- what felt overwhelming will now feel much more manageable.


    Another way to
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    manage the fear of venturing out on your own is to start small. If the thought of just up and quitting your day job frightens you, start building your client base on the side. Begin with low-risk steps and gradually work your way up to the harder
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    stuff.


    Remember, courage is not a matter of losing your fear so you can take action; courage comes from taking action. And that, in turn, helps you overcome your fear. When you can act despite your fears, you will be rewarded many times over.


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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