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Non-wovens are defined as flat structured fabrics, such as sheets or webs, not made by weaving but

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

by bonding and entangling fibers by means of mechanical, thermal or chemical processes. The major

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

non-woven technologies now available, are needle-punching, thermal-bonding, air laid, spun-bonding,

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

melt blowing and spun lacing/ hydro-entanglement.

The non-woven materials produced under these pro

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

esses are extensively used for technical applications such as surgical gowns, diaper cover stocks,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

utomotive linings, and military applications such as decontamination wipes and geo-textiles such as

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

insulating tank/lake bunds. India, firmly well-established in commodity textiles such as apparel

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

/made-ups at the rear of its tough cotton economy, has to promote itself into high-value products s

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ch as technical textiles/non-wovens. Non-woven textiles inside the overall technical textiles is

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ikely to grow globally at an average 8 per cent, with the Asia-Pacific region being expected to sho

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

a vigorous 9.6 per cent annual escalation rate between 2006 and 2009.

The world production of non

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

-wovens elevated from 2.16 million tones in 1994 to 4.43 million tones in 2004 with a probable valu

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

jump from $9 billion to $15.9 billion, correspondingly, during this period. Europe and North Ame

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ica, which had the lion's share of 1.35 million tones and 1.16 million tones, respectively, in 2004

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

world production figure of 4.43 million tones, may give way to the Asia-Pacific region, which is pr

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

jected to increase its non-woven products productivity from 1.02 million tones in 2004 to 1.67 mill

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ion tones by 2009.

At present, the total volume of non-wovens produced from India is estimated at

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

5,000 tones, as compared to China's non-woven product output of 7.55 lakh tones (China is a dominat

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ng force in non-wovens among the Asia-Pacific region and the third largest non-woven producing regi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

n after America and Europe because of life-style changes, the rising middle-class, and its economy)

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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