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This is an update to the original article about the Page Rank 10 Experiment where the page rank 10

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

web site tries to achieve a Google page rank of 10 within 2 years. The participating site that ref

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rs the most traffic to the page rank 10 site gets to keep the page rank 10 site at the end of the c

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ontest if it achieves the page rank level of 10.

The Page Rank 10 Experiment is continuing to grow

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

but is it meeting with any success? Ultimately, it seems only logical that the success of this pr

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ject can be measured but only in one way, the page rank that it actually achieves.

The site starte

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d on April 20th, 2006 and as of today, January 20, 2007, it is currently showing 2540 back links in

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Google. New sites continue to sign up as participants in this experiment on a regular basis.

One

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

an only wonder what will be the ultimate outcome of this attempt to achieve an unthinkable and most

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

likely unreasonably objective of a page rank 10! I don’t know how many sites currently rank as a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

R10. Google owns the only sites I can recall matching this page rank level.

As of this writing th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

site reports 111.799 unique visitors since 4/20/2006. The last time I wrote about this, they were

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

predicting an increase in page rank from PR4 to PR6. I have personally seen that Google has updat

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

d its page rank for at least some sites since the last article I wrote about this.

The page rank o

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

the page rank 10 web site did not increase during this update. It is still registering a page ran

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

k of 4. Owning a web site with a page rank of 10 would open up huge opportunities for the new owne

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

.

But, even if it were to occur, how long could it actually achieve this page rank? Probably not

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ery long as the incentive for other sites linking to this site would be gone once there was a new o

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

wner.

Stay tuned for more updates on this experiment in the future and visit The Pixel Wars to fin

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the link to this page rank 10 experiment site. It is the green banner that says pagegrank10 on it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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