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Transportation refers to the physical distribution of finished goods, from the place of production

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

to the place of final consumption. It also includes the transportation of raw materials to the plac

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

of production. Logistics aims at reducing the cost incurred during transportation by employing sci

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

entific methods and customized software.

Transfer of raw material and finished goods can be done t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rough roads, railways, airways, sea routes, canals and high capacity pipelines. The selection of a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

particular medium depends on the nature of the product and its shelf life. Perishable goods like fl

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

wers, fruits and vegetables need a faster medium of transportation like air and road. Ships are us

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ed to transport items like metal, crude oil etc.

The reduction of transportation costs is calculat

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

d by selecting the shortest distance between two points and the time taken to travel. Goods are now

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

tagged with Radio Frequency Identification (RFID) tags to keep track of their location. Even truck

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

are fitted with GPRS systems to help drivers find the destination in time.

Logistics companies us

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

transportation software to make the most efficient use of their existing fleet of trucks, ships, a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nd cargo planes. They also help other companies by providing them with technical expertise and cust

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

mized systems that improve efficiency. Transportation is important especially for large multination

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

al companies. Products of these companies traverse large distances over land, sea and air to reach

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

their place of consumption.

With the growth and acceleration of the global economy, the freight tr

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ansportation industry faces greater challenges and demands. Extensive research on transportation an

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

logistics is carried out on a regular basis. A new research is studying the natural ability of ant

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s to find the shortest route between two points. Institutions like the American Society of Transpor

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ation and Logistics help companies improve their supply chain and reduce their transportation costs

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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The essence of the double entry accounting system is the analysis of each transaction in terms of the basic accounting equation: assets = liabilities + owner's equity. Many smaller undertakings and organisations maintain only minimal accounting records and do not have a system whereby transactions may be analysed and recorded within the framework of the double entry system, often referred to as a single entry accounting system.

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