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Are you a distributor, reseller or wholesaler of goods? As a distributor, your biggest

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

accomplishment – getting a very large order – can turn into a nightmare if you don’t ha

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ve the financial resources to deliver it. Why? Because if you don’t fulfill the order,

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ou risk losing your client.

But there is a simple solution to this problem, and you wo

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

n’t find it at your local bank. It’s called PO financing. PO financing provides you wit

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

the necessary financing to buy the goods from your suppliers, deliver them to your cus

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tomers and close the sale.

And you can use PO financing even if your company doesn’t h

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ve credit. How? By using your purchase order from a strong customer (or the government)

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

as collateral. It’s an ideal tool that can help a company grow past its current financ

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

al limitations.

Let examine a sample PO financing transaction. It usually has 6 steps:

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

You get a PO from your client
The po financing company pays your supp

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

liers via a bank wire or letter of credit

The order is delivered to your client

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

who accepts it

You invoice your client

Your client pays the invoice,

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

concluding the order

The transaction is settled

Although PO financin

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

is a great tool, it is not for everyone. Given the associated risks, most po financing

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

companies will only finance transactions that:

Sell goods/products that are m

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nufactured by a 3rd party

Sell goods to reputable clients or government entitie

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Have profit margins of 25% or more

If you meet these criteria ther

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

is a big chance that PO financing will be able to help you. And an additional benefit

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

of PO financing is that is relatively easy to obtain and can be set up in a week or two

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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