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The pop-up style expandable frame display has now been in existence for over 15 years. It is the most common portable display now on the market. The first were made of a flexible fiberglass frame, with aluminum channels ba

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rs and roll able fabric that was attached to the framework with magnets. The basic design has not changed over the years, but the options this technology offers has. The frame expands to a large size, allowing a full 10' w

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ide exhibit to be transported in a relatively small case. The case also contains the fabric, lights and vertical bars allowing for the fabric or photo-mural panels to be attached. Most 10' pop-ups , in their case weigh und

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

er 90 pounds complete. There now are many manufacturers of many types, the most common being a 10' width display described as follows:

A. Standard Grade Popup - includes lighter weight aluminum frame, individual a

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

luminum, PVC or steel channel bars, Velcro (Frontrunner or Prelude) fabric panels and thermo molded shipping cases with wheels. They are quite common; usually incorporate two 200 watt halogen lights, and a case of some ty

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

pe that can be converted to a podium. They are a standard ten foot wide curved design. The price ranges for the standard curved models in a ten foot width run $995-$2995, depending on the vendor.

B. Commercial Grade Po

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

pup - includes heavy weight frame with nylon connectors, folding steel channel bars, Velcro (Frontrunner or Prelude) panels and the choice of 1 or 2 thermo molded shipping cases with wheels. Less common, as they are mo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

re expensive, they also come in different shapes, straight or curved, and in many widths. There are only a few brands that may be labeled "commercial" as the tendency of the marketplace has been to make the pop-up exhibit

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

lighter and less expensive to own. They are more for companies that exhibit often, with different employees setting up the display each time. They can take far more abuse than the standard type pop-up found for sale everyw

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

here on the internet. The price ranges for these types run $1795-$3495, depending on the vendor.

C. Photo Mural Grade Popup - A standard grade popup with the substitution of photomural panels instead of the Velcro

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

fabric panels and includes everything in the standard grade pop up. These are still standard pop-ups, but have a greater appeal as they have powerful large-format graphics on the front, attracting attention. They are more

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

expensive, because of the photo panels, but still are just as portable. The customer has to be careful here as many types of panel printing can be offered, from the most expensive DURST LAMBDA to inexpensive ink-jet proces

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ses. The prices run from $2195-$5995, depending on the vendor and the print process.

D. Fabric Mural Grade Popup - A popup curved or non-curved frame with a replaceable fabric graphic mural. The fabric mural is pr

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e-attached to the frame, making set-up much easier than the standard pop-up with photomurals. This display offers a full photomural effect without a cumbersome set up procedure. It transports in a lightweight nylon bag, h

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ard shipping case and lights are usually available. These weigh less than half of what standard 10' pop-ups weigh. The graphic face usually gets wrinkled in the bag, but his can be remedied by the owner with stretching and

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

steaming. The print process needed for these types is important also, as they are generally viewed as a lower quality graphic than what is found on standard pop-ups. This may not be the case, depending on the vendor. Pric

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

es for these pre-attached models with fabric faces run $1695-$4995, depending on the vendor and print process.

E. 3-D Style Pop-up - These are the newest entries to the pop-up market. They essentially are the fabri

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

c style pre-attached graphic pop-up only with a twist. They have the graphics attached to the framework to give a three dimensional effect, also incorporating different frame shapes, from square to round to trapezoidal. Th

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e graphics are already on the frame, making set up of these types very easy. The graphics are also easily removable/ replaceable with costs being low. They run from $995-$8995 depending on the shapes, numbers of graphics a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nd vendors print process used.

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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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As the head of training, I was a team member of a cross functional team organized by a pharmaceutical company to address ways to increase field force effectiveness. At the time the team was organized the company was surpassing sales goals, however, recognizing that within three years the company would begin to face loss of patent protection, increased ...

Distribution logistics play a valuable role in any warehouse distribution system. Every warehouse is unique, and thus has its own unique distribution logistics. It can be something as simple as the number of floors or something as complex as the computer system used.

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