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    “Absolutely, Positively, Overnight, Guaranteed”

    “Reach out and touch someone”

    “VISA: It's everywhere you want to be”

    All memorable promotional slogans, right? But how did these tiny phrases work for these BIG companies, to help position and promote their service? That’s the real question.

    Federal Express was
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    perceived as just another shipping company. But they were very smart: they did market research. And what they found was that most shippers were not on time, and did not have viable tracking systems. Customers of those lesser shippers, therefore, were often angry, since their packages were lost or delayed. With
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    that in mind, FedEx created a system that was extremely revolutionary for its time: hub shipping, which required that all orders be processed in one, centralized location. By activating a large fleet of planes and trucks (and people!), FedEx was able to meet the demand for guaranteed overnight service—at a time
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    hen our culture as a whole was infusing speed to provide an edge in business. Now, of course, we can surf the Internet faster than we can talk. But back then, such a significant move to highlight FedEx’s differences from other shippers, and promote that difference “absolutely, positively,” convinced even us toug
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    h skeptics.

    Working in the film business at the time, we typically spent over a half-million dollars just to shoot one commercial or television episode. Naturally, we were reluctant to trust our original celluloid film to some shipper who might not temperature-protect it, thus ruining the image quality. Worse,
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    e certainly couldn’t contract with a shipper who might lose the film entirely, and wasn’t insured to reimburse us the half-mil needed to re-shoot our film. Sure, now we can digitize a copy, or use a dozen other protective measures, but back then it was a very different techno-time. In our industry, the productio
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    n cost was so incredibly prohibitive that we only hired people or equipment that “absolutely, positively” could get the job done, like FedEx.

    Looking back on those times, the ad slogans reveal lessons not in clever wording (as most companies mistakenly believe is the key), but rather in great thinking. After al
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    l, as we’re fond of saying, Knowledge is Bliss! Understanding what clients really need, and how your company can fill that niche, is the key to capturing ongoing business from satisfied clients. And it’s not just applicable to giant corporations, whose slogans we know so well. Small companies need intelligence t
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    find out how they’re different, so they can really embrace and promote those differences.

    EXAMPLE OF HOW IT WORKS One of my clients, Kathleen Kline & Associates, has a virtual office from which she provides transcription and editing services. She was selling against similar types of companies in her area. Onc
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    e we surveyed her clients, we discovered that they valued the differences that set her apart from the plethora of other, less intellectually sophisticated editors and transcribers.

    Therefore, we promoted her "Intelligent Virtual Office" services and raised her rates to be commensurate with the value she brought
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    to her clients.

    Kathleen's elite education (Dipl?me Sup?rieur from the Sorbonne in Paris), as well as her ability to understand and accurately transcribe technically complex subject matter from audio-taped interviews into real text, using the clients' actual words (as opposed to transcribers who simply employ p
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    honetics, which yield impossible-to-understand or completely useless transcripts) greatly distinguished her company's value from her competitors.

    If you need a great, cost-effective transcriber, editor, or proofreader, I'd be glad to put you in touch with Kathleen Kline & Associates. She can tell you firsthand
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    how her revenues jumped from embracing her differences and promoting that.

    CLEVER IDEA FROM A SMALL COMPANY Patricia Griecci, CEO (and “Top Dog”) of the “Smiling Dog” company, makes products for “Kids with Tails”. What are her products? Dog cookies. Is there a market? Yes! As a matter of fact, ten million peop
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    e regularly purchase such products. The idea for her business came to Patricia when she was trying to find a really nice dog bed for her own “kid.” She now thinks of herself as the “Martha Stewart for dogs.”

    At a professional conference a few years ago, Patricia described how she found and successfully filled t
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    his need, explaining, “Go for the void. When you see a need, do your due diligence to make sure there’s a market, and then create a niche product. Don’t take ‘no’ as never, but instead as a ‘not now’ answer.”

    WHAT TOP LEADERS TEACH US IN MARKETING Because I’ve been fortunate to work in television, taping thous
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    nds of business and community leaders, politicians, scientists, educators, entertainers, athletes, and a cross-section of humanity, I’ve gathered some wisdom from them that directly applies to marketing. These noted professionals mostly concur that if one is to be recognized and remembered, and hopes to succeed,
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    one is obligated to put forth the following principles.

    · Stand up for your beliefs with integrity, passion and imagination. Don’t be afraid to be different—that’s what will be “absolutely, positively” remembered about your company!

    · Be authentic in your messages—steer clear of hype, spam, and ho-hum marketi
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ng. Putting out that kind of drivel is insulting, and no one has time for it. Be clear, authentic, and consistent. Success is noisy—the phone is ringing! So, be sure to listen to your intuition while it’s noisy and you’re reaping profits, because that’s what will guide you to keep your business thriving.

    · Your
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    brand is your promise. Stick to it, and consider its DNA as your own.

    · None of us has all the answers. Find experts or those more knowledgeable than yourself to help you—consultants, mentors, coaches, lawyers, friends, kids, a board of directors, or whatever works. (This is also hugely stress reducing).

    · How
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    you think is more important than what you know. When you need someone knowledgeable and thoughtful to help you think things through, don’t be afraid to ask for counsel (yep, that’s what we do here).

    · It’s easy to make changes, because so few of us do.

    · Knowledge is Bliss. When you have it, you’ll enjoy life


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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