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Just Other Articles - 5 Keys to Choosing Plate Rolls
Unfortunately, many buyers end up purchasing equipment that lacks the capability and flexibility to meet production volumes and tolerances, simply because they don't understand all available options and considerations.
Between diminishing factory orders and increasing labor and energy costs, companies that use plate metal in their fabricating processes are fin
Between diminishing factory orders and increasing labor and energy costs, companies that use plate metal in their fabricating processes are fin
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ding their profit margins increasingly pinched.
Yet, manufacturers must still invest in new production equipment -- whether to replace obsolete equipment or to take advantage of new business opportunities -- in order to remain competitive.
Manufacturers must make careful assessments when evaluating the addition of new plate-rolling equipment. Debt capital is
Yet, manufacturers must still invest in new production equipment -- whether to replace obsolete equipment or to take advantage of new business opportunities -- in order to remain competitive.
Manufacturers must make careful assessments when evaluating the addition of new plate-rolling equipment. Debt capital is
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
still available to purchase new machinery, but paying back the loan will not yield a satisfactory return on investment unless the equipment adds value to the production.
In an effort to help manufacturers optimize plate rolling operations, 5 key considerations are offered in order to choose a proper plate bending machine.
1. Work with an equipment dealer that
In an effort to help manufacturers optimize plate rolling operations, 5 key considerations are offered in order to choose a proper plate bending machine.
1. Work with an equipment dealer that
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
is willing to discuss your specific plate-rolling needs
Customers must know the correct questions to ask, in order to get the correct answers. Each manufacturer faces unique challenges, and through systematic querying an astute sales representative can determine exactly what equipment will work best for their process.
Customers need to discuss issues such as
Customers must know the correct questions to ask, in order to get the correct answers. Each manufacturer faces unique challenges, and through systematic querying an astute sales representative can determine exactly what equipment will work best for their process.
Customers need to discuss issues such as
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
inside diameters, material type, tolerances and the desired shape of the finished product. As an example, some products, such as those found in the pressure vessel industry, demand a maximum of 1 percent out-of-round on their diameters or they are considered defective. By using an underpowered plate roller, too much of a barrel effect can render such a product
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
useless and quickly erase any potential profit margin.
Manufacturers must also carefully consider whether they wish to roll conical or parabolic shapes to take advantage of a broader market. Hydraulically operated four-roll machines are ideal for this type of work by eliminating surface scarring, thereby decreasing the need for grinding the lamination (bullno
Manufacturers must also carefully consider whether they wish to roll conical or parabolic shapes to take advantage of a broader market. Hydraulically operated four-roll machines are ideal for this type of work by eliminating surface scarring, thereby decreasing the need for grinding the lamination (bullno
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
sing) on the minor diameter edge of a cone.
Accurate conical rolling is further achieved through features such as torsion bar parallelism, as opposed to electronic systems or proportional value systems that merely maintain a theoretical balance. Finite parallelism allows the machine to be adjusted to its full conical tilt and back to parallel in only five seco
Accurate conical rolling is further achieved through features such as torsion bar parallelism, as opposed to electronic systems or proportional value systems that merely maintain a theoretical balance. Finite parallelism allows the machine to be adjusted to its full conical tilt and back to parallel in only five seco
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
nds.
Matching plate-rolling equipment to the specific needs of a manufacturer requires attention to detail. It is imperative that the dealer you work with is willing to sit down with you and discuss the specific needs of your business. There are many issues that need to be addressed, many of which a purchasing manager may not initially foresee.
2. Factor in t
Matching plate-rolling equipment to the specific needs of a manufacturer requires attention to detail. It is imperative that the dealer you work with is willing to sit down with you and discuss the specific needs of your business. There are many issues that need to be addressed, many of which a purchasing manager may not initially foresee.
2. Factor in t
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
he properties of the material to be rolled
A metal's temper and yield strength must be matched with the customer's application to correctly determine the specifications of the plate roller. This is especially important since steel characteristics have changed drastically over the past couple of decades. What was once known as mild steel no longer exists.
Even
A metal's temper and yield strength must be matched with the customer's application to correctly determine the specifications of the plate roller. This is especially important since steel characteristics have changed drastically over the past couple of decades. What was once known as mild steel no longer exists.
Even
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
though drawings call for a plate to be rolled down to the same dimensions, a tougher material will require a much higher-rated rolling machine. In absence of such considerations, defects will result and the manufacturer will end up with excessive scrap.
Today's steel is much stronger and requires more strength to bend. Thanks to detailed classifications by th
Today's steel is much stronger and requires more strength to bend. Thanks to detailed classifications by th
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
American Society of Mechanical Engineers, countless varieties of steel abound: A36, A516 grade 70, Hardox 400/500 series and AR 200/300 series, for example. And these different steels require varying pressures to roll.
3. Carefully consider bending diameters
All machines achieve precise measurements at 50 percent of the full-rated value. Therefore, given a 1
3. Carefully consider bending diameters
All machines achieve precise measurements at 50 percent of the full-rated value. Therefore, given a 1
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
.1 roll geometry, a 3/8-inch machine with a 10-inch top roller can consistently roll 3/16-inch plate to 11-inch ID without any barrel defect.
As a rule of thumb, most machines can roll plate at 1 1/2 times the upper roll diameter. Hence, given a 10-inch-diameter top roll, inside diameters as tight as 15 inches can be obtained. However, new machines that incorp
As a rule of thumb, most machines can roll plate at 1 1/2 times the upper roll diameter. Hence, given a 10-inch-diameter top roll, inside diameters as tight as 15 inches can be obtained. However, new machines that incorp
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
orate planetary guides are able to keep approximately 50 percent more area of the plate under bend-pressure during the rolling operation, thereby achieving ratios of 1.1 times the upper roll diameter. This creates a 30 percent advantage on tight diameters.
The tighter the diameter, the more bend pressure required. For instances where thick material must be rol
The tighter the diameter, the more bend pressure required. For instances where thick material must be rol
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
led into tight inside diameters (ID), the diameter of the top roll and the layout of the machine can make the difference between a product whose cylindrical edges meet and one that won't close.
4. Incorporate both side and vertical supports to prevent unwanted bends
When rolling a cylinder, once the inside diameter is more than 200 times greater than the thic
4. Incorporate both side and vertical supports to prevent unwanted bends
When rolling a cylinder, once the inside diameter is more than 200 times greater than the thic
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
kness of the material, the weight of the material becomes sufficient to bend the cylinder as it exits the top roll and gets further away from the machine. Without proper support, unwanted radii result.
Purchasing a machine with both side and vertical roller supports easily solves this problem.Some manufacturers attempt to skimp on this ancillary equipment by r
Purchasing a machine with both side and vertical roller supports easily solves this problem.Some manufacturers attempt to skimp on this ancillary equipment by r
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
esorting to "makeshift" support such as a forklift or overhead crane. However, this shortcut ties up the use of equipment that can best be utilized elsewhere. Because it cannot adequately support the material, unforeseen bends can still appear.
Adequate support requires both side and vertical roller-supports, as designed by the manufacturer of the plate-rollin
Adequate support requires both side and vertical roller-supports, as designed by the manufacturer of the plate-rollin
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
g machine. Once employed, plate rolling becomes a one-man job instead of two. This frees up valuable manpower that can be re-routed to other jobs.
5. Stay within ideal operating parameters of the machine
It is recommended that manufactures identify what material and what thickness represent their highest volume of work. Then (a company) can deliver a machine
5. Stay within ideal operating parameters of the machine
It is recommended that manufactures identify what material and what thickness represent their highest volume of work. Then (a company) can deliver a machine
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
that will camber to that specification, thus conserving valuable production hours and eliminating large amounts of scrap.
Quality rolling machines are usually cambered at 50 percent of the full-rated value of the machine. Hence, a 1-inch machine is cambered to roll 1/2-inch plate at a nearly perfect edge.
Disregarding this important fact can result in out-of-
Quality rolling machines are usually cambered at 50 percent of the full-rated value of the machine. Hence, a 1-inch machine is cambered to roll 1/2-inch plate at a nearly perfect edge.
Disregarding this important fact can result in out-of-
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
spec product that the customer will not accept. Problems most commonly arise when rollers attempt to push the upper limits of their plate roll. If 5/8-inch plate is rolled through a 1-inch-rated machine, a small degree of barrel effect will likely occur. This may or may not be an acceptable margin for error.
However, when plate thickness approaches the upper e
However, when plate thickness approaches the upper e
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
nd of a machine's rating, then severe defects can occur. Unless corrected with a shim, it will not be sellable. Conversely, when very thin material is rolled through a machine rated for very thick plate, the finished product may come out tighter in the center than at the ends. Again, time consuming shimming is necessitated to correct for this "hourglass" effect
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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