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Energy prices continue to rise, but projects to save energy can pay for themselves and put money in your pocket.

Did you know?
· Energy efficiency improvements provide savings for their entire product life, pe

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rhaps up to 20 years, well past the point where the savings have paid for the initial improvement.
· Improvements in energy performance and employee comfort can increase income due to improved productivity, per

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

haps as much as 10 times as high as the energy cost savings produced by performing the upgrade.
· Many energy efficiency improvement programs pay for themselves in less than 3 years.
· Improved comfort res

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ults in improved retention; in retail stores, shoppers stay longer and are more likely to make a purchase; and in industrial settings, there are fewer absences.

Energy efficiency improvements aren’t rocket science,

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

but it does take some specialized knowledge. Studies regularly show that the money for the upgrade is already in most operating budgets but is being used to pay high utility rates due to inefficient use of energy

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

resources. Let’s take a look at a hypothetical property and see how this works.

Given a 20, 000 SF owned facility with annual energy costs of $10,000 (building A) and an 80,000 SF owned facility with $90,000 annua

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

l energy costs (building B), we find that:
· Building A costs $0.50 per square foot for energy
· Building B costs $1.13 per square foot for energy.
· If we want energy savings of 15 and 30%, respecti

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

vely, Building A provides a potential annual savings of $1500 and Building B provides a savings of $27,000.

The annual cash flow is $28,500. With an interest rate of 5%, a 7 year term, and a decision to use 90% of

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the savings for energy investments:
· You can finance energy projects equal to $151,000 without increasing the capital and operating budgets, and the budget contributes $1.51 per square foot for energy improve

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ment.
· The simple payback period is 5 years 4 months; savings begin accumulating beyond that point.

If you lease, it still can work to your advantage. Let’s say that you have the above property on a three-ye

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ar lease.
· You can finance energy projects equal to $69,000 without increasing the capital and operating budgets, and the budget contributes $0.69 per SF for energy improvement.
· The simple payback is

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

2 years 5 months.
· Not only do you pay for energy improvements today using the money saved from future bills, but you also are saving money before the end of your lease period.

Tenants in leased facilities of

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ten are concerned that the landlord reaps a no-cost benefit of having a more energy efficient building. After all, he or she is getting an increase in asset value of the property and an environment that leads to in

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

creased tenant satisfaction and retention. Most forward-thinking landlords will see their benefit, and agree to some sort of cost sharing approach; others may respond by lowering rents and other tenant costs.

Addi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tional analysis can be done using more advanced tools that help determine the best time frame to do the project, the effect of different interest rates, the internal rate of return, and so on. The important thing to

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

remember is that energy improvements last well beyond the payoff date, and savings continue to grow from that time forward.

For the leased property, and going back to the plus points, this means that even a 10 yea

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r service life generates a cumulative cash flow of over $230,000 and that improvements in employee productivity could yield an additional $690,000.

Here are the results from a couple of properties in Oakland County

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

, Michigan:
· A 68-unit apartment complex was able to improve electrical energy efficiency by 39% and gas use by 10 to 25%. The upgrade will pay for itself through energy savings in just over 3 months, and the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

owner will save over $2300 every year on energy costs.
· A 21,000 SF industrial site owner can invest up to $27,000 in energy upgrades without affecting his capital or operating budgets. Payback through energy

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

savings is in less than 3 years; energy efficiency improves by over 35%, and he saves over $9600 every year after the project is completed.

It’s easy to choose to invest in energy efficiency when you know the facts

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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This article describes the importance of hiring a real estate agent, particularly in the Boston area. A real estate agent can facilitate the buying and selling process a number of different ways.

Buying a Franchise is a complicated business investment. Generally the way most franchising agreements stand in modern day business you are leasing a business rather than buying one for a specific term. Most consumer awareness websites and even the government regulatory bodies recommend before taking the plunge and buying a franchise that you have a Franchising attorney look over the Uniform Franchise Offering Circular or UFOC.

You have heard the old adage 'walk a mile in my shoes.' How about walking a mile alongside yourself? What would that be like? What would it be like to be your own employee, a client or even your boss?

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