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Microsoft does not know a heckuva lot about presentation design, but one thing they do correctly in PowerPoint is to make available different types of graphs so that you can match the graph type to the point you’re trying t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

o make with your data. There are twelve different graph types available with PowerPoint 2000, but few of those styles work well in the low-resolution world of computer-based presentations. With few exceptions, here is how

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ou want to use the following types:

• Pie Graphs for Share

• Bar Graphs for Comparative Amounts

• Line Graphs for Trends, Time

Pie Graphs

Pie graphs (commonly misnomered pie charts) are one of the more overused, and

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hence misused, types of graphs, primarily because they are so easy to make, and easy to make look good. They are misused when chosen to show amounts rather than share. The beauty of pie graphs is that they show so clearly

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

what they are supposed to show, i.e., how much of the whole each element contributes. In most cases the actual amounts – in this case percentages – are actually secondary to the area of the slices in terms of telling the

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tory.

When you look at a pie graph with five or fewer slices, your brain can quickly ascertain which groups dominate. We often see pie graphs with more than 5 elements, but they then become more difficult to comprehend in

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

short order. In most cases, consider whether your story needs to include details about all the players, or whether a group of insignificant contributors can be grouped as “others”.

If you want to show how much volume each

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

element contributes, rather than what fraction, you’ll want to use a bar graph.

Bar Graphs

To show relative sizes of different segments as well as the actual amounts, you’ll want to use a bar graph. Bar graphs are desig

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ed to show volumes against a y-axis that clearly delineates the units of measure. By having a series of bars next to each other, we can see how each element compares with the others as well as what absolute volume the elem

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nt represents.

There are variations on the bar graph, such as a stacked bar, where different elements are stacked on top of each other to form a series, or a 100% bar graph, where all the bars are the same height but are s

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

lit to show what percent of the whole the volume reflects. In a presentation environment, esoteric options are best to be avoided.

Line Graphs

Line graphs have the unique advantage of speaking to inherent right-brain prej

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

udices about information. That is, when typically conditioned western minds see a graph with no labeling, they automatically assign “volume” to the y-axis, with “up” meaning “more”, and a time-line to the x-axis, with the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

eft side meaning most recent. Just as we read from left-to-right, rightward motion subconsciously means positive motion.

You would want to use a line graph, then, to show a progression in amount from one point in time to

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nother. The elevation of the line at any one point represents the quantity of the tracked data at that moment. Audiences, wanting to be the first-to-know, will automatically make assumptions about the types of values x-ax

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

es and y-axes represent. Don’t disappoint them.

Data labels

Graphs are a great way of making complex information easily understood. But graphs work best only when you properly integrate words, numbers and images. Whene

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

er possible, label the elements of your graph directly on the elements themselves, rather than relying on the ever-popular clarity killer, the legend. Legends require too much effort on the part of listeners to discern exac

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ly what each data point is. Just be certain your labels don’t clutter up the otherwise clear “picture” a good graph can make.

If you have a number of graphs in your presentation, you’ll want to avoid dumping a data overloa

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

d on your audience by over-labeling each one. In fact, in many cases you can tell your story forcibly enough by only the size of your data elements, without burdening their minds with numbers that they’re likely to forget

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

y the end of the presentation. However, it’s also not a bad idea to have what we call “reference slides” that do contain all the data attached to the end of your main slide deck. To really impress your crowd, install hyp

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

rlinks to these slides from the ones in your main show, and when some vice-president makes a stink about wanting to know the whole story, zap to your total-info slide and give him what he wants. He probably won’t ask again

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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