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Managing energy is not just about food. It's about managing working conditions that affect how your body releases energy. This includes managing stress, oxygen levels, exercise levels and food breaks. Work de

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

mands can zap energy very quickly so you need to have a few tricks up your sleeve to boost your energy supply to help you both physically and mentally.

The Brain Protein Continuum

The neuro

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s in your brain are largely made of fat. The brain cells communicate with each other using neurotransmitters. Neurotransmitters are made up from amino acids; protein building blocks. Another important amino a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

cid is tyrosine.

Eating protein increase levels of tyrosine in the brain, helping the brain generate nor-epinephrine and dopamine. These chemicals promote alertness. The absorption of protein is assisted by

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

arbohydrates. So eating a balanced supply of carbs and protein throughout the day will keep that brain network humming and avoid that 3pm black hole.

Top 10 Work Day Energy Guidelines

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

li>Start the day well rested - Treat your bed as an important energy re-supply station and ensure you book in long enough for the process to be completed. That means 7 to 9 hours a night.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Try a workout first thing - even 20 minutes will boost your bodies oxygen supply and keep your head thinking straight longer during the day. It's often much harder to feel inspired at the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

end of the day. If morning isn't your thing - the evening can still work. Try tricking yourself. Change into workout gear as soon as you get home. Switch on the television or put on a DVD, and instead of hea

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ing for the couch, sit on a workout bike or yoga mat with some weights. A few seconds later the brain starts connecting the visual messages and before you know it an hour has gone by.

Keep th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e body supplied with fuel - Eat a small, healthy snack every few hour of lean protein and whole grain carbs. The carbs provide a rapid energy release, while the protein provides longer-lasting energy

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Keep the body well hydrated - air conditioning is extremely drying on your system, and that includes the brain.

Take an oxygen break - if you don't have time

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

for a full lunch break, take at least a 10 minute walk around the block or anywhere where there is more oxygen than car fumes. I use walking catch-ups. If a staff member wants to chat about something briefly

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

I get us both out for a walk.

Try boosting energy during the day - some deep breathing [preferably not whilst on the phone to the CEO]; taking the stairs instead of the elevator or ju

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t standing up doing some leg raises all help to move oxygen around the body and boost the cells energy producing processes. I keep a small hand weight on my desk and it's amazing what you can do during a phon

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e call!

Keep good energy nutrition snacks at work - protein balls are my favourite. I make them on Sunday and they last the whole week in the refrigerator. [that is if I don't eat the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

all by Thursday]. I use them for my 3pm low zone snack and as a mental pick-me-up before entering a long meeting.

Reduce the alcohol during the week - try getting it down to one glas

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s a night - you will be amazed how much easier it is to get out of bed in the morning and you will be more likely to feel like doing that early morning workout. And your skin will look fantastic!

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ng>Go easy on the coffee - caffeine is not a good long term solution for energy throughout the day. It's addictive and better left to one cup first thing in the morning. You will sleep better also.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

li>

Reduce the size of your evening meal and avoid carbs after 6pm - you will find you will sleep better and that translates into more energy during the day.

And if you want to

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ontribute to the worlds renewable energy supply - take a leaf from enterprising gym enthusiasts like Doug Woodwring who are harnessing energy created from everyday workouts and converting it into usable power

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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