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I went shopping for clothes today.

My plan was to buy a navy blue sports coat, a couple of shirts and ties and maybe a pair of black shoes.

Understand t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

hat as a sales trainer, I want people to ask me to spend my money. I'm not going to buy unless asked. Unfair you say! Maybe but here's the thing... Unless

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

you ask me to buy, I won't.

How hard would it be for me to spend maybe $1,000? As it turned out, it was very hard. Let me recount what happened.

Store

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

. A well-known CBD menswear store. Actually they were having a sale - up to $200 off sports coats. I went to the display, took a coat off the rack and put

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

it on. A size too small. A well-dressed, well-groomed senior staff member came up and said there was one in the next size and gave it to me. I tried it o

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and it fit and looked good.

Reduced to $399 and there's me with cash in my pocket... I said I wanted to look at shirts so he put the coat back and left

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

me alone. Taking two shirts, I went to the tie rack and picked out two nice ties. Then I took them back to the coat rack and held them next to the coat.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Talk about giving out buying signals!

I was completely ignored. All they had to do was to say, "Great selection - they go together really well. Was there

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

anything else you wanted?" and over $700 would have found its way into their cash register.

I left the store with my wallet intact and no new clothes.

S

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

tore 2. Drove from the CBD to a suburban mall. I knew the store I was going to; found the sport coat rack and tried one on as two staff members watched. I

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

looked at myself in the mirror, went to get a shirt and tie and held them up in the mirror too. No one spoke to me. I was there for ten minutes and again

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

left with my wallet intact. Of note was that there were no other customers in the store at the time.

Store 3. A little more down-market this one - a guy

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

with a purple open-necked shirt hanging outside his pants (looking like the host from a reality TV show like "Idol").

He saw me hovering around the coats

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

and asked me if I knew my size. I told him and he showed me where they were, giving me four different colours and styles to try on.

He was really helpful

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

, explaining fabrics and what to wear with them. I politely told him that they weren't quite what I was looking for so what he did next was to refer me ba

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

k to store 2 where he said they had "better brands"

No sale. Three times I'd tried to spend several hundred dollars. I went home with the money still in

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

my wallet.

No one asked me why I was buying the clothes; what I was planning to wear them with or where I was planning to go when wearing them. No one at

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tempted to get my name for their list. No one bothered to ask me to buy. It's so simple, it's annoying.

Oh, and guess what else? Not one of them made any

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

attempt to get my name, address, or email details. So none of them offered me the opportunity to hear in advance of new ranges, summer / winter sales. Mis

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

sed opportunity.

Please understand, I don't want to be sold, I want to buy but I sometimes need help. Here's the message: If you don't ask, you won't get

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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