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Internal business structures have been radically transformed over the past few decades. Changes in areas such as communication and transportation technology and shifts t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

owards global interdependency have resulted in companies becoming increasingly international and therefore intercultural.

In addition, the need to ‘go global’ and to cu

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

outgoings is demanding that companies combine protecting international interests whilst keeping down staff numbers. The solution in most cases has been the forming of i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ntercultural teams.

As with all businesses, success depends upon effective cooperation and communication within teams. The intercultural dimension of today’s teams howe

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

er brings with it new challenges. Successful team building not only involves the traditional needs to harmonise personalities but also languages, cultures, ways of think

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ing, behaviours and motivations.

Intercultural teams have an inherent disadvantage. Cultural differences can lead to communication problems, unpredictability, low team

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ohesion, mistrust, stress and eventually poor results. However, intercultural teams can in fact be very positive entities. The combination of different perspectives, vie

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ws and opinions can lead to an enhanced quality of analysis and decision making while team members develop new skills in global awareness and intercultural communication

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

In reality this best case scenario is seldom witnessed. More often than not, intercultural teams do not fulfil their potential. The root cause for this is that when in

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

tercultural teams are formed, people with different frameworks of understanding are brought together and expected to naturally gel. Without a common framework of underst

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nding, for example in matters such as status, decision making, communication etiquette, this is very difficult and thus necessitates outside help to commix the team.

In

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

tercultural or cross cultural training is one method of helping to blend a team together. Through analysis of the cultures involved in a team, their particular approache

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

to communication and business and how the team interacts, intercultural team builders are able to find, suggest and use common ground to assist team members in building

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

harmonious relationships.

Intercultural training sessions look at helping a team to realise their differences and similarities in areas such as status, hierarchy, deci

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ion making, conflict resolution, showing emotion and relationship building. These are then used to create mutually agreed upon structures of communication and interactio

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

n. From this basis, teams are then tutored how to recognise future communication difficulties and their cultural roots, empowering the team to become more self reliant.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

he end result is a more cohesive and productive team.

In conclusion, for intercultural teams to succeed, managers and HR personnel need to be attuned to the need for in

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tercultural training to help cultivate harmonious relationships. Companies must be supportive, proactive and innovative if they wish to reap the potential benefits inter

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ultural teams can offer. This goes beyond financing and creating technological links to bring together intercultural teams at surface level and going back to basics by f

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ostering better interpersonal communication. If international businesses are to grow and prosper in this ever contracting world, intercultural synergy must be a priority

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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