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Recent research at the University of Texas and Washington State University in the United States and Surrey University in England ha

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s revealed that distributing plants throughout the office workplace can both lower stress and enhance employee productivity.

In th

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e Texas experiment, participants were tested while using a computer program that had been specifically created for the test. The te

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

sting was done in cubicles that had been designed to replicate the average office environment. Participants were shown a series of

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

random symbols, and were then monitored according to their stress level, based on blood pressure, and their productivity based on r

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

eaction time.

The tests were then run in environments with and without the common types of interior plants that are often seen in

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

office cubicle situations. The results of the Texas study showed that participants were less stressed and had better reaction times

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

when the plants were present. A computer program to test productivity and induce stress was specifically designed for these experi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ments. One hundred symbols were presented in identical randomized sequences to each test subject, and the only variable in the test

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

was the presence or absence of plants.

Plants were positioned in such a way that they could be seen within the peripheral view of

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

subjects as they sat at a computer terminal. Besides being able to concentrate and react more quickly, the study showed that simpl

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y having plants within view increased subjects' ability to react by as much as 12 percent, as well as enabling them to recover from

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

stress within five minutes.

Almost identical results were obtained in a similar study conducted at Washington State University, u

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

sing essentially the same testing procedure. When plants were placed around the sides of a cubicle, subjects felt less stress (as i

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ndicated by lower systolic blood pressure levels) and just as UT researchers had discovered, the WSU study showed that subject reac

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tions were some 12 percent faster while they were taking a carefully-standardized computer test.

A third study, conducted at Engla

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nd's University of Surrey, examined the effect of strategically placing plants around an office in order to reduce noise levels. Pl

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ants were found to significantly reduce noise, thereby increasing productivity among employees. Although it's somewhat difficult to

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

quantify, most office workers are familiar with the effects of noise pollution firsthand. If you work in an office, just think bac

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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