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Imagine if you could make a dollar every time you handed someone a special sheet of paper. To earn the dollar, all you would have to do is get people to read that sheet of paper.

Normally, you

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

would think that making money in this fashion would be a great thing. However, you would soon find out that you’d have a very big problem on your hands: copycats.

Generate huge amounts of cash

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

or yourself and people will always take notice. Not only will they copy your business model, but they will do anything they can do make their business look good while making your business look b

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

d.

Enter the infamous paid survey site. Websites that claim you can make big bucks by taking a few surveys online every now and then.

It wasn’t long ago when I first saw one of these sites and

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

thought to myself: “Wow, what a great way to make a little extra cash for myself.”

Little did I know, this was just one of a million other survey sites out there basically offering the same typ

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

of deal. I was under the impression that the site I joined was reputable and unique.

That couldn’t be further from the truth. Hundreds, if not thousands of these paid survey sites exist. Unfor

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tunately 99% of them are exactly the same.

Why so many clones you ask? It’s because paid survey sites are similar to the “sheet of paper” example that I mentioned earlier. Paid survey sites are

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

a profitable business and they are incredibly easy to copy.

Let’s take an example:

Joe spends a Sunday afternoon surfing the web and stumbles across a paid survey site. He reads that he can ge

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

paid for his opinion by taking surveys online. All he has to do is pay an upfront membership fee to access the database of companies who send out the surveys.

Joe signs up, pays the membership

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

fee, takes a few surveys and makes a few extra bucks. Joe then becomes aware that this paid survey site business model works like a charm. It was able to convince him to pay to access the direct

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ry, so why wouldn’t it be able to convince other people?

Joe then decides to create a survey site of his own. He already has the big list of survey companies from the site he previously joined.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

The only thing he has to do is register a domain name, purchase a web host, put a page together and voila: a new paid survey site is born!

So now, not only does Joe receive money from the surv

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ys he’s taking, but also from the upfront membership fee he charges his visitors to access the exact same list of survey companies that got him started in the first place!

Each person that sign

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

up at Joe’s new website represents yet another possibility that he or she will take notice of this survey site business model and create one them self.

Thus you can see just how quickly these

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ypes of sites are copied. They really do multiply faster than bacteria!

But what does this mean for you?

Well, quite frankly, you’re getting ripped off. Not only are these paid survey sites co

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ycats of one another, the list of companies that they charge you for is actually available for free!

Yes, you read that right. These survey companies are not classified C.I.A documents. They’re

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

out there on the web to be found. They’re just looking to do market research and they need help from people like you to give opinions on their products.

The trouble lies in knowing where to fi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

d these companies. That’s where these paid survey sites enter the picture. Upon paying the membership fee, you are given access to a huge, neatly organized list of companies that send out the su

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

veys.

But I would wager you would have an uneasy feeling inside your stomach knowing you’re paying for something that you know is freely available. Am I right?

Those were my feelings as well,

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

o I decided to do some legwork and create a website listing some of the top survey companies without charging a fee upfront to access them.

After all, not everyone wants to be known as bacteria

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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