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Domain is the name of the website, as in www.websitename.com. Domain registration is the proce

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ss by which the regulatory body, the Internet Corporation for Assigned Names and Numbers (ICAN

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

), registers the names of the websites in its Domain Name Server (DNS) database. It not only a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

llocates the new names to the websites upon request, but also ensures that all domain names ar

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

unique, and the database is available for everyone to see. The latter part of the website add

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ess, such as com or org is referred to as the top-level domain. This gives a general idea abou

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t the website and who owns it. For instance .gov means that the website is owned by the govern

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ent, and ?.com? means it is for commercial purpose.

Initially, when the Internet was set up,

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

by just providing the IP (Internet Protocol) address, websites could be accessed. An example o

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

what an IP address looks like is 420.92.11.76. An IP address is unique to every computer, jus

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

like a phone number or an address. However, as the number of users increased, it was not logi

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

cal to expect users to remember number combinations. Therefore, the naming system was brought

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n place, by which websites would have their names, which were easy to remember. In 1993, the I

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nterNIC (Network Information Centers) was set up, whose job was to maintain a database of doma

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

n names and their respective IP addresses in the US. Each country has their own NIC that are r

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

sponsible for allocating the domain names. In the US now, although there are a number of Regis

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

trars that provide domain names, Network Solutions maintains the central database.

Each count

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

y has its own top-domain, for instance .uk for United Kingdom and ?.in? for India. Re-registra

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tion of domain is required every 2-5 years.

Websites such as http://www.domaintools.com provi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e a link to the database, where the International availability for domain names can be checked

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.justotherarticles.org.ua/article/59160/justotherarticles-International-Domain-Registration.html">International Domain Registration</a>

BB link (for phorums):
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If you want to increase quality and dramatically save costs in production, then, yes, the road to perfection is definitely worth the driving time.

The best salespeople are those who can identify the gap that exists between a prospect's current situation and the ideal situation, widen the gap, and then provide solutions to bridge that gap.

It's the ability to engage in quality conversations that sets high-performing teams apart. And there are significant commercial advantages, too - not least, better decision-making, improved efficiency and delivering organisational change more effectively. Team Performance expert Philip Houghton has come up with the key questions leaders must ask their teams. Part 2 covers questions about capability.

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