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Global Domains International is rated #37 of the top 500 fastest growing privately held companies in the USA. What this means is that this company is successful. For the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

customer it means they can trust in this company and ensure their website is secure. Global Domains International sells domain names and hosts websites. They have capital

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ized on a unique idea that has moved this company quickly into the forefront of the world wide web.

A domain name is a websites address. The domain name extension is the pa

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

rt at the end, dot come, for example. Website addresses are used instead of IP address which are a long series of numbers that would be difficult to remember. A typical

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

website address looks something like this: www.onlinewebsite.com or in the case of Global Domains International the website address would look something like this: www.onl

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

inewebsite.ws.

When the internet first became largely popular everyone was using domain names ending in dot com. The founders of Global Domains International, Michael Ree

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d and Alan Ezeir realized that finding a domain name extension other than dot com would become something valuable. They looked at the country codes assigned to each count

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ry. For example, the United States has dot us and the United Kingdom has dot uk. They focused on a small country that had yet to capitalize on their domain name extension

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

- Samoa. Samoa is a small country in the South Pacific with a population of less than 200,000.

There domain name extension is dot ws. Mike and Alan immediately recogniz

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ed the marketing potential of ‘ws’ when used as an abbreviation for website.

The reason a good alternative to dot com was needed is that as more people began publishing we

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

bsites the available names with the dot com extension were dwindling. That made it difficult for a business or person to register the domain name they really wanted. Even

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

tually all the good, easy to remember and logical dot com domain names would be taken. The extension ‘ws’ was perfect because it is easy to associate with the word ‘websit

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e’. This is what Michael and Alan recognized and why they set out to convince the country of Samoa that they could profit from their country code.

Michael and Alan met wi

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

th leaders in Samoa and with the local technology company who had the rights to the code. They told them how they could make a profit off the dot ws and how beneficial it

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

could be to their country. They also explained how they would sell the dot ws domain names. The leaders agreed and allowed Michael and Alan to use the dot ws extension.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Global Domains International quickly took off. The Samoa government told Michael and Alan that they would need to sell 15,000 domain names in the first three years in orde

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r for them to continue using the domain extension. This task was completed in the first month. Today Global Domains International has sold domain name registration to lar

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ge companies like Yahoo! And Intel. The Samoans receive a percentage of sales and is pleased with the partnership with GDI.

GDI has been so successful because it fills a

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

need. The dot com websites soon did become obsolete and other domain name extensions were needed. Mike and Alan have created a user friendly product and offer templates a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nd hosting to help customers build their website. Global Domains International is at the top of its industry because of the hard work and dedication of Michael and Alan.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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