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    Sending email messages seems pretty easy but all too often users put themselves and their personal contacts at risk
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    from spammers. How? lets look at the issues;

    Selecting recipients

    TO: sends a message to the stated email addres
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    , all emails in this section are visible by the recipient

    CC: stands for carbon copy and is the same as the above,
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    the only reason for using it is to indicate the MAIN RECIPIENT(S) are shown and secondary people sent CC - all emai
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ls are visible.

    BCC: stands for blind carbon copy - copy an email sent with TO and perhaps some CC email addresses
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    to people so that the main recipients do no know who was sent BCC. This route is best for mass mailings of contacts
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    from your address book.

    Someone who receives an email sent TO and/or CC can click REPLY ALL and email all the othe
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    rs emailed regardless, this way spammers can pick up on a personal email with dozens perhaps hundreds of email addr
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    sses.

    Remember a spammer need not be someone who sends millions of emails but anyone who sends promotional commerc
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    al email unsolicited, this could be someone sending hundreds of emails a day picked up from CC emails. Low volume s
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ammers are often more difficult to detect, although they do send the SAME message, it is usually to a smaller more
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    select set of emails, perhaps with some common theme or interest (pet owners, visitors to France etc)

    Account Iden
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ities

    If you use a computer based email client such as Outlook or Outlook Express you can create several different
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    identifies with a single ISP account. You do this my creating a replica of your email account (with the same login
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    details and password) but change the REPLY TO email address and Names to suit different needs.

    Why do this? there
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    re a host of reasons;

    # You own or manage a number of web sites and want to reply from EACH by for example having
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    n account for say XYZ.COM you can appear to reply from that domain and create a more professional image.

    # You may
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    want to mail friends and special contacts using your own REAL email or special reserved email account.

    # Differen
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    people may use the same computer and email account - each can have its own email account.

    Note: Most ISPs allow y
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    u to create a number of emails with a single user account or if you have a web site unlimited prefixes.

    And finall


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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