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There are several specific ways that you can nichefy your existing list. The first, one I have already

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

discussed, is simply asking your list what their wants and needs are, and then begin to meet specifica

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

lly those needs. Now one thing that will happen is that some people will unsubscribe from your list as

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

your offerings become more tightly themed, but the increased revenue from the subscribers who stay on

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

your list should eclipse the lost revenue from the ones who drop from your list. Do not be overly conc

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

rned with the ones that leave your list; be more concerned that you are streamlining your list so that

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

it makes you more money. Remember what you are in this business for, and constantly measure what you a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

re doing against that goal.

The second way that you can nichefy your existing list is to send out a fr

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ee gift to your list, one that would only appeal to subscribers that already belong in the tighter nich

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e. So for example, with the pet products example, you could send out a free gift titled “How to Train

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

our Dog to Sit in 10 Minutes Flat”. Now, for the most part, the only people who are going to download t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

hat manual are going to be people who have dogs, not cats or goldfish, etc.

Now, when they click to do

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

wnload that gift, set up an autoresponder page so that in order to download the manual, they have to op

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t in to your dog-lovers list. Now, you will be building a list of dog-lovers specifically. You can al

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

so take the additional step of removing them from the general list, or you set up your autoresponder so

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

that it excludes them from receiving your general offerings if they are on the tight niche list. How y

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ou structure that will probably depend a lot on how your autoresponder works; you can email your autore

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

sponder company and find out the best way to separate the niche mailings from the general mailings. Yo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

u certainly don’t want this new niche list to start receiving multiple emails because they are on multi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ple lists; if you are not careful with that you will get unsubscribes and lower open and response rates

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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