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You’ve been running your ezine for a while now, maybe a few months, or a few years. And it’s getting dull, people are unsubscribing, new subscribers are few and far between. What you need is to put the Oomph! Back

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

into your newsletter!

It’s easy to get into a rut once the whole e-newsletter thing is old hat. It happens to the best of us, but there’s no need to let boredom set in and ruin all that hard work. Let’s take a loo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

k at some of the most common mistakes made by ezine publishers and how to fix them.

• Reusing Content. Obviously, it’s easier to republish a few articles here and there, but what you might not realize is that any

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

older subscribers will rapidly lose interest. They will assume (perhaps correctly) that you have no new information to impart and will unsubscribe!

How to Fix It: Always, always give your readers fascinating new c

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ontent. Running short on time? No problem, just hit a few free article directories and pull some new articles from your topic area. I don’t recommend doing this all the time, some original content is always a good

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

dea, but it’s a quick fix.

You might also consider investing $10 in original articles if you have a couple of days before the deadline. Go to a freelance writer’s job board and post an ad looking for writers. Many

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

writers are more than willing to write short articles for $3-5 and can usually have them done within 24 hours. Ask to see samples, though, to make sure you are getting good quality.

• Too Many Ads. I’ve seen far

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

too many ezines (and print magazines, too!) get into the habit of adding more and more ads to their publication as time goes on. While subscribers will be fine with a couple of extra ads, it’s never a good idea to

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

fill your ezine up with banners and links. It devalues the content you do have and your subscribers will lose interest.

How to Fix It: Easy, limit your ad space. If you’re selling ads, keep it down to one main ad

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

or banner plus three to five classifieds. If you are including affiliate links, make sure you only include relevant ones and keep them to one or two per ezine issue. You should never have more than 20% of your cont

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nt comprised of ads.

• Fluff. We’ve all done it at least once, included a bunch of nonsense fluff just to fill up a newsletter that had to get out in an hour or so. Subscribers will lose interest and trust almost

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

immediately if they get an email that contains essentially 0 content.

How to Fix It: Keep a file full of extra articles and tidbits for those last minute deadlines. You can write them in your free time, or even ju

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

st save interesting, relevant information that you find while surfing, to be converted into a story later on.

If you really don’t have time to write, then spend five or ten minutes a day checking out free ezine ar

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ticle directories and copy one to three articles into your file (complete with resource box) for later use.

• Too Much Personal Info. Another trap that is easy to fall into is to write about yourself instead of fi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

lling your ezine with quality content.

How to Fix It: Unless you are writing a family newsletter, personal information should be limited to a couple of paragraphs. Sure, it’s good to connect with your readers, but

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

at the same time, you need to give them the information that they signed up to receive.

By simply fixing these common mistakes, your ezine will be back on top. But what if you want to add even more Oomph! to your

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ezine?

Something new will always grab your readers’ attention, so why not try a new section? You could add a small piece where you review the latest books or software related to your topic or maybe a Q & A column.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Use your imagination, or, if that doesn’t work, ask your readers what they would like to see added to your ezine!

Another idea to consider is to take out a current section that has just gotten too difficult to wr

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ite. If you can never think of a new problem to address in your “Troubleshooting Basics” column, it might be better to drop it than to keep recycling the same info.

Use your readers. Ask them for their opinion on

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

your ezine, what sucks, what could be better, what is their favorite feature. You’ll be amazed at the suggestions you get and how implementing even one or two of the most popular ones will make your ezine pop again

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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