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If you’ve been in the business very long, you know that if you have

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

300 subscribers new on your list, that some number of them—whether it

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

’s three of them or ten of them, but some consistent number over time

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

—is going to buy your product, whether it’s a $10 product or a $100 p

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

oduct.

And once they purchase that one, if you have another one, you

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

do the same thing, and you track this over time, you will learn exac

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tly what percentage of people will buy the next product that you’re o

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ffering.

Now, what happens is, if you have a—for example, a $10 prod

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ct, and then a $47 product, and then a $100 product, and then a $500

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

product… let’s imagine that you only have the first two. You have a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

$10 and a $47 product. Now, the people that have just purchased your

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

$47 product, some percentage of them—unbeknownst to you, some percen

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

age of them—would purchase the next product in line, if you had it av

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ailable.

Because you don’t have it available, they don’t buy it from

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

you, but because they need it, they’ll buy it from someone. They’d

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

rather buy it from you, they like you, they trust you, that’s why the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

’re already buying from you. The sooner you can—it’s the sooner you

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

can create that next product, the more you’re going to be able to com

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

pletely and fully monetize the people on your list. And obviously on

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ce that $100 purchase is made, then there’s a bigger purchase in line

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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