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Link exchange nowadays is under very *precise* view of search engines. Major search engines are very keen on telling natural link building from unnatural.

Your

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

link exchange will look super suspicious to search engines if you do not know how to use anchor texts.

Anchor texts should be different during li

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nk building!

It seems illogical, at first sight; because the aim of any link exchange is to get as many backlinks with your keywords as anchor text as

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

possible. So, on the surface, if you want to grab 1st position in Google for 'car loans' you must get as many backlinks with 'car loans' in anchor text as possib

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

le.

But in real life this logics will fail you, because you have to look on this problem as search engines do. Otherwise don't expect good positions from search

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

engines if you don't play by their rules.

For search engines it looks super unnatural if all the anchor texts of all your backlinks are

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

the same. Search engines 'think' (and, by the way, they are right) that if your site gained backlinks naturally, at least some anchor texts should be: 'click her

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e', 'click this link', 'here', 'more info here', 'learn more about it here'.

Maybe, 3-5 years ago search engines would never care about this. But now there are

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

many solutions that automate link building, and good solutions can help you build over 100 links per day. And for search engines it's a problem, because good sol

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

utions will build good links, and for search engines these links will look very nice. And it means those who have these solutions have advantage over those who d

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n't have them. So, actually search engines are fair about giving a favor to the sites that build links naturally, and - on the contrary - put to watch list the s

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ites that manipulate with links shamelessly.

How to look natural?

The answer is simple. When building backlinks, make sure that portion of y

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

our anchor texts are not your keywords, but a mixture of 'click here', 'learn more here' and other *junk* words that inevitably appear when you get backlinks nat

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

urally.

For example, you want to get good position for 'car loans'; in your place I would use these anchor texts: 'car loans', 'good car loans', 'car loans here

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

', 'click this link'.

Surely, make accent on your keywords (otherwise - no sense to build links), but diversify them. Make up to 10-20% of your backlinks to hav

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

texts that don't have your keywords inside anchor.

What is the ideal percentage?

Forget this question, don't kid yourself. Search engines wil

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

l never disclose the percentage of links that should have 'click here' and other 'junk' words inside. That is why - don't even try to find ideal percentage.

I w

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ould recommend you to mimic real life. In my experience, from 5 to 30% of natural backlinks contain 'junk' words. And it's up to you to d

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ecide how many links should have your keywords in anchor. Just bear in mind that you should look natural. And when you look natural, search engines will never af

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

fect you with their changing algorithms, because search engines will never fight natural sites.

Be wise, be natural, and enjoy the results of your link exchange

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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