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Most web site owners know that the number of links pointing to your site (link popularity) is very important. However, often the source of thes

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e links (link quality) is overlooked.

That is why it is essential for every web site owner to continually monitor both link popularity and link

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

quality. Using a tool such as the Checker and Link Quality Checker from Elixir Systems will give you the necessary statistics on your links and

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

your competitor's links.

Here are some of the statistics you should monitor:

Total Inbound Links to your Home Page
Most sites linking to

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ou will be to you home page. This statistic should show the total links both including and excluding internal links.

Total Inbound Links to You

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

Whole Site
You should know the total amount of links going to you whole site. This is a good figure to compare with competitor sites.

Qu

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

antity of Deep Links
These are links to pages other than the home page. These links are a valuable indicator of the quality of a site. Bou

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ht links tend to go to the home page whereas organically grown links tend to go to internal pages. These internal pages get a boost from these o

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

fsite links and are an often overlooked by web site owners.

Deep Linking Percentage
The deep link percentage is the number of deep links a

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

a total of the overall links. This generally ranges from 5% to over 80%. Having a deep link percentage of over 30% appears to indicate a nicel

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

linked site. This is the minimum you should strive for.

Yahoo Directory
Does your site have a link from the Yahoo Directory? One of th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e most important directories on the internet currently is the Yahoo directory. The Yahoo directory is seen as a trusted link and is worth more t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

an links from most other sites. The nice thing about Yahoo is you can get a link fairly easily for the price of submission. Once in the Yahoo di

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ectory it’s not uncommon to see 40 or more links listed here as your site will be listed in all English language Yahoo directories i.e. Singapor

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

, India, UK, Ireland, etc.

DMOZ Directory
The other important directory is the DMOZ directory. This directory is used by Google. Unfortun

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tely it is currently extremely difficult to get into DMOZ.
Links From .gov and .edu Sites
Links from .gov sites and .edu sites are ver

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

y valuable. These sites carry a harder level of entry and more importance.

Pages Indexed
If you do not have inbound links the search engi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

es cannot index your site. However, there may be other technical reasons why your site is not being indexed by one or more of the search engines

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

Therefore you should monitor how many of your site pages are indexed by each of the three major search engines Google, Yahoo! and MSN. In addit

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

on you should look out for the search engines indexing both the www.sitename.com and sitename.com sites which can cause duplicate content issues

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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