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    When having a responsive email it is vital to ensure that simple steps are taken to en
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    sure professionalism at all times. Whether it is an automotive response email or a per
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    sonal response email you should follow simple grammar rules. An email is the same as a
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    letter.

    1. The Email should have a heading, a body, and a closing. These three points
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    should NOT be missing. If possible use the person’s name that you are responding to.
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    Begin by thanking them for their Email and then respond accordingly. When concluding t
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    e body, again thank them for their time and Email. You can never thank them enough! An
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    d then use a proper closing. Keep your Email short and to the point. Stay on track wit
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    h what the subject pertains to! Try not to be too broad or vague. Use simple language
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    nd be respectful at all times. Explain terminology, even if you feel that they would b
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    e aware of what you are discussing.

    2. If the responsive Email is automated, it is im
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    portant to appear professional as well. Address key points in the email. Thank them fo
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    their inquiry, provide an adequate time line of how and when they will be responded t
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    o and if possible provide alternate means of communication for further inquires (a tel
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ephone number or other Email address).

    3. If the responsive Email is a personal Email
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    it is again important to appear professional. Address the specific question or comment
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    by restating what the sender addressed. This will remind them of the subject and prov
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ide trust that you addressing specifically their concern or care. Provide all the rela
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    ed information that will answer the question or concern. If possible provide additiona
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    l resources and contact information. Thank them for their time and then end your email


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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