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A lot of Google AdSense publishers are banned from the Google AdSense program for click fraud. Some of these Google AdSense publishers manage

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

to get their AdSense account reinstated. However, majority of them failed to do so. As a result, they are banned from the Google AdSense progr

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

m.

Google does not reveal any specific details on how they define click fraud. They do not disclose their proprietary click fraud detection t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

echnology as well. As a result of that, publishers would not be able to report any click fraud activities on their website.

However, Google d

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

es provide general definition of invalid clicks. It may be a good idea to learn how they define invalid clicks and how they detect click fraud

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

.

Google defines invalid clicks as:

Manual clicks intended to increase publisher's advertising
Clicks by automated tools, r

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

bots, or other deceptive software.

So how does Google detect click fraud activities on your website? How would they know which cli

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

cks are invalid? Google AdSense team uses three powerful tools to detect invalid clicks:

Detection and Filtering Tool
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
: Each click on an AdSense ad is monitored by Google system. Google will record the IP of each click, the time of the click, duplicate clicks
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
and various click patterns. Google will use these factors and filter out potential invalid clicks.

Advanced Monitoring T

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ol: Google uses its proprietary software to monitor click fraud activity. They are constantly working to improve their click fraud de

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ection technology.
The Google Team: In addition, Google has a team that uses specialized tools and techniques to exa

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

mine individual case of click fraud. When Google system detects potentially invalid clicks, a member of this team will examines the affected a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

count.

There are few innocent publishers whose AdSense account has been terminated because of a sudden spike in their AdSense earni

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ngs. This sudden jump in AdSense earnings is due to the sudden jump in website traffic. The spike in their AdSense earnings would probably rai

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e the red flag in Google click fraud detection system and had their accounts terminated. If you think your AdSense account is terminated unfai

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rly, Google provides you a way to make your appeal:

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

l" target="_blank">http://www.google.com/support/adsense/bin/request.py?contact=invalid_clicks_appeal

A Piece of Advice

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

When you are making your appeal via email, you should stay calm and plan the right strategy. You should be patient when dealing with Google a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

d most importantly you should be polite when communicating with them. You may take initiative to provide them with all the documents they need

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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