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One of the keys to obtaining top rankings, or ANY rankings for that matter is making sure that the search engines can properly spider and index your site. This means doing whatever you can to make sure the search engines ar

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e able to reach each page of your site as easily as possible.

When I talk to my clients about spiderability, I'm generally referring to two things...

1) Are all the links in the site true hyperlinks that can be picked up

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

roperly by the search engines.

2) Are all the pages within the site reachable within 2-3 clicks from the homepage.

So let's go over the above two areas of concern.

1) Hyperlinks. This may seem almost silly, but you would

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

be amazed at the number of sites I run into when doing consultations and website analyses that have non-standard hyperlinks. By "non-standard", I'm referring to javascript generated hyperlinks or hyperlinks embedded within

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lash files.

There is nothing inherently wrong with javascript or flash when used properly, but that simple fact is that javascript and flash are NOT search engine friendly. Google is pretty much the only engine that is abl

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to pick up links within javascript or flash code. At this time, I have seen no evidence that either Yahoo or MSN have this ability.

While Google may be able to pick up links, it is unclear as to whether or not Google plac

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

s any VALUE on the links it finds in this manner. Remember, much of a pages ranking in Google is determined by links so you want to be absolutely sure that each and every link is valued.

So, be absolutely sure that your li

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ks are true hyperlinks (by "true" hyperlinks, I'm talking about hyperlinks coded with the normal href tags) if you want to make sure they are found, followed, and counted by all the engines.

2) Distance from Homepage. Idea

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ly, you want your visitors and the search engines to be able to reach any page within your site within a maximum of three (3) clicks and preferably two clicks. The more clicks it takes to reach a page, the less chance ther

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

is that the search engines will index that page.

It is for this reason, that site maps have become so popular. By utilizing a sitemap, you are able to link from your homepage to a page that lists all or most of the links

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

o the various pages of your site. The search engines (and visitors) are then able to get to virtually any page of your site within just a couple of clicks.

You'll notice I've mentioned not only the search engines but the v

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

isitors as well in the above paragraphs. By reducing the number of clicks it takes to get from your homepage to any page on your site, you will find that you also increase the overall usability of your site.

While site map

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

can definitely help to increase the spiderability of a site, it is important to remember that they are not a total fix for bad navigational structure within a site. As mentioned, all of the search engines utilize a pages l

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nk popularity in one way or another in their algorithms.

In general, the homepage of a site will have the highest link popularity of any page within the site. This is because most inbound links to a site are pointing to th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

homepage. It's from the homepage that all the internal pages derive their link popularity from a sort of "trickle down" affect.

A site map will only derive a certain amount of link popularity that it can pass on to the pa

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

es it links to. To understand this best, think of the homepage as a large river with each link on the homepage a smaller river branching off from the main river. Each river will be fed a similar amount of water by the main

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

iver. Alone one branch of the river will never be able to deliver as much water to the various areas as all the branches of the river can combined.

The site map is one branch of your sites link popularity river and it has

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

alue, but it will never have the same impact as a well throughout and implemented links structure that makes use of all the rivers of link popularity within your site.

To make the most use of the link popularity of your si

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e, you should try and setup your sites navigational structure so that even without a site map, the search engines and visitors are STILL able to reach any page within your site within 2-3 clicks.

So...to make a long story

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

hort...Always be sure to utilize true, standard hyperlinks throughout your site and be sure that your sites navigational structure allows any page of your site to be reached within no more than 3 clicks.

See you at the top

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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