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The jury of search engine experts over at SEOMoz has weighed in, and here are the top factors affecting search engine placement, according to them, with my comments.

1. Keyword Use in Title Tag - I have s

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

aid for many years that if I had a gun to my head, and could do only one thing to a web page to optimize it, my choice would be the title tag. Put your keyphrases in your title tag, and remember to optimiz

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

each page individually (i.e. don't overstuff your title tag, and have different title tags for each page that reflect the content of that particular page - otherwise, you may suffer from a duplicative con

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ent exclusion and find yourself in the supplemental results).

2. Keyword Use in Body Text - Duh. If your keyword or keyphrase isn't mentioned at least once in the body text of the web page, then it does n

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t seem your page is very relevant to that keyphrase, now does it? But don't get all caught up in the keyphrase density myth - there is no magic number of times it should appear. Make sense to readers, and

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

t will make sense to the search engines.

3. Relationship of Body Text Content to Keywords (Topic Analysis) - Google is smarter than you give them credit for, and just stuffing a keyphrase into a completel

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

unrelated page won't do you much, if any good. Your page should be on a topic which is semantically related to the keyphrase which you are targeting in your title tag.

4. Keyword Use in H1 Tag - Oh, for

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

years the naysayers have been telling me that H1 tag keyphrase use meant nothing and that I was an idiot for thinking otherwise. Well the verdict is in and this is the fourth most important factor accordin

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

to the SEOMoz article. At this point, therefore, we have learned to put your keyphrase in your title tag, include it in your body text, which body text is topically or semantically related to the keyphras

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

, and head up the body text with an H1 containing the keyphrase.

5. Keyword Use in Domain Name - This is one that I disagree with. I have seen absolutely no evidence of this at all. Do a simple search on

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

he internet for most any search term, and chances are the top results do not have the search query in the domain name. I believe this may have minor importance, but don't go and change your domain because

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

f it. Seriously, you have much more to lose (such as age of domain, inbound linkage, site reputation, etc.) I regularly see clients at the top of Google with domain names containing nothing near the releva

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t search terms.

6. Keyword Use in Page URL - This is what I have called "descriptive file naming" for a number of years. I believe it is of some importance, again, however, is more of a factor when settin

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

up a new domain than would be for an existing domain with high pagerank and inbound linkage. Changing your internal url's for the sole purpose of meeting this criterion again is very risky, for the same r

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

easons mentioned above.

7. Keyword Use in H2, H3, H... Tags - Well if it works for H1, why not for H2 et al.?

8. Keyword Use in ALT Attributes and Image Titles - SEOMoz incorrectly calls them an ALT tag,

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

but it is not a tag, the ALT is an attribute of the IMG tag. Semantics aside, I believe this to be highly important, I would have ranked this above the URL and domain name items. Experience has shown me th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

t image optimization (image file name, alt attribute, and title) is a wonderful way to make a page more relevant to a desired search query.

9. Keyword Use in Bold/Strong Tags - I always use this method, a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

well as keyword use within the EM (italics) tag. I believe this to be a moderately important factor as it helps emphasize to Google what your page is about, and what you consider important. Definitely on

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

y short list of things to do for "on page" search engine optimization.

10. Keyword Use in Meta Description Tag - Again, one of my "big 4" for on page optimization. The "big 4" being: title tag, meta descr

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ption, h1, and image ALT attributes. (I don't include body text in my big 4 as I believe that is self evident). Definitely important, and again, each page should have custom title and meta description tags

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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