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Just Other Articles - Four Color Printing - Is It Worth The Price?
Four-Color printing can add a, exciting dimension to your marketing materials that can be much more dramatic than simple one or two-color printing. One or two-color printing is not necessarily inferior to four-color, but the question should be: is four-color printing really necessary for the project on hand?
For example, a direct mail piece or marketing brochure that is introducing your company for the first time to a potential customer should make a great first impression and four-color printing may be the best way to communicate your products or services. However, an assembly instruction b
For example, a direct mail piece or marketing brochure that is introducing your company for the first time to a potential customer should make a great first impression and four-color printing may be the best way to communicate your products or services. However, an assembly instruction b
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ooklet to be included with a product may work fine as a one- or two-color printing project.
Four-Color Pros:
Many clients and designers often feel that four-color process printing gives them the most design flexibility. With four-color process printing, any color imaginable can be created, allowing the designer to make text in color or to use graphic elements for emphasis that literally jump off the page.
Photographs can be reproduced in color, making product images much more believable and many different colored screen tints are possible giving a designer an almost limitless palett
Four-Color Pros:
Many clients and designers often feel that four-color process printing gives them the most design flexibility. With four-color process printing, any color imaginable can be created, allowing the designer to make text in color or to use graphic elements for emphasis that literally jump off the page.
Photographs can be reproduced in color, making product images much more believable and many different colored screen tints are possible giving a designer an almost limitless palett
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
e to work with when designing.
If you are trying to produce a show-and-tell brochure where photographs are vital to explain a service, process or product, then four-color process printing is your logical choice, regardless of the price.
Four-Color Cons:
Four-color printing is usually considered much more expensive than one and two-color printing. Generally, the same brochure quoted as four-color versus two-color can easily be as much as 200-400% more expensive since there are four printing plates involved, and there is a lot more pre-press work involved.
While printing costs have b
If you are trying to produce a show-and-tell brochure where photographs are vital to explain a service, process or product, then four-color process printing is your logical choice, regardless of the price.
Four-Color Cons:
Four-color printing is usually considered much more expensive than one and two-color printing. Generally, the same brochure quoted as four-color versus two-color can easily be as much as 200-400% more expensive since there are four printing plates involved, and there is a lot more pre-press work involved.
While printing costs have b
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
ecome much more competitive over the last few years as more printers have gone to digital printing (with digital files outputting directly to plates), the pre-press work is still quite involved, though much of it is now done by graphic designers, instead of by printers.
If you have photographs or transparencies, they will need to be scanned, though digital photography does eliminate the need for scanning. Color images will still need to be color corrected and in some cases, some work will need to be done in PhotoShop to improve a photograph's contrast and clarity.
Other pre-press work may i
If you have photographs or transparencies, they will need to be scanned, though digital photography does eliminate the need for scanning. Color images will still need to be color corrected and in some cases, some work will need to be done in PhotoShop to improve a photograph's contrast and clarity.
Other pre-press work may i
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
nclude converting photograph files from RGB to CMYK and making sure all images are sized properly and have adequate resolution for printing.
Simple one or two-color printing jobs have less pre-press work and fewer plates to be made, and tend to be less expensive to print than four-color.
Trying to reproduce some PMS (Pantone Matching System) colors using four-color process can be difficult if not impossible with some colors. Often a client will have a logo or design element that has been printed on past materials as a PMS spot color and are upset when the same color cannot be created accura
Simple one or two-color printing jobs have less pre-press work and fewer plates to be made, and tend to be less expensive to print than four-color.
Trying to reproduce some PMS (Pantone Matching System) colors using four-color process can be difficult if not impossible with some colors. Often a client will have a logo or design element that has been printed on past materials as a PMS spot color and are upset when the same color cannot be created accura
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
tely using four-color process.
Most four-color printing requires coated paper stock in order to produce the best color fidelity. While you can print four-color process on uncoated and textured stock, many clients find the softness and lack of contrast of the printed reproductions to be less than desirable when uncoated stock is used.
Often it is necessary to varnish or apply liquid lamination to large four-color areas or large solid areas in order to limit finger printing, especially on brochure and pocket folder covers. This is sometimes viewed as an option, but is really necessary to make
Most four-color printing requires coated paper stock in order to produce the best color fidelity. While you can print four-color process on uncoated and textured stock, many clients find the softness and lack of contrast of the printed reproductions to be less than desirable when uncoated stock is used.
Often it is necessary to varnish or apply liquid lamination to large four-color areas or large solid areas in order to limit finger printing, especially on brochure and pocket folder covers. This is sometimes viewed as an option, but is really necessary to make
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
sure a quality piece makes a great first impression.
Four-color printing also requires proofing of all color proofs prior to printing to ensure true color fidelity, and it is a common practice for the client and designer to be present during press runs to approve all color and supervise press adjustments if necessary.
Pre-Press—Where Things Go Right—Or Wrong
There is an old saying that you should use the right tool for the right job, and with creating pre-press files for your project, this is very true.
When you are producing high-quality, offset lithography materials, there is no
Four-color printing also requires proofing of all color proofs prior to printing to ensure true color fidelity, and it is a common practice for the client and designer to be present during press runs to approve all color and supervise press adjustments if necessary.
Pre-Press—Where Things Go Right—Or Wrong
There is an old saying that you should use the right tool for the right job, and with creating pre-press files for your project, this is very true.
When you are producing high-quality, offset lithography materials, there is no
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
substitution for high quality graphic design tools such as the Adobe Creative Suite (Illustrator, InDesign, PhotoShop) and Quark XPress. There are some other applications that can be used, but these are the most widely used, because they are designed to work within the exacting color standards and protocols demanded by four-color printing.
If you talk to printers, you will find that few, if any, are willing work with client-provided files such as Microsoft Word, Publisher and other programs that are aimed at creating basic documents. More often than not, these applications are just not compa
If you talk to printers, you will find that few, if any, are willing work with client-provided files such as Microsoft Word, Publisher and other programs that are aimed at creating basic documents. More often than not, these applications are just not compa
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
tible with the software and output devices used by printers.
Programs such as Adobe InDesign and Quark XPress, are designed to be compatible with the software and standards used by lithographers, and will provide for greater flexibility and accuracy for everyone throughout the pre-press and printing process.
Check with the printing company you will be working with before you start designing your project to see what programs and file types they prefer to work with.
Achieving Color Quality
Avoid doing pre-press work yourself unless you have the pre-press expertise or an experienced r
Programs such as Adobe InDesign and Quark XPress, are designed to be compatible with the software and standards used by lithographers, and will provide for greater flexibility and accuracy for everyone throughout the pre-press and printing process.
Check with the printing company you will be working with before you start designing your project to see what programs and file types they prefer to work with.
Achieving Color Quality
Avoid doing pre-press work yourself unless you have the pre-press expertise or an experienced r
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
esource to do the work for you. A pre-press professional will have calibrated monitors so there is less of a chance of color problems, and they will have a work flow process so they can make sure all pre-press elements work together. Digital files delivered to a printing company need to work together flawlessly so there are no surprises after the job is printed. Also, four-color process printing is very exacting—what may look fine on a desktop printer may be blurry and lifeless when printed by offset lithography.
You should work through a graphic designer who has a lot of printing experience
You should work through a graphic designer who has a lot of printing experience
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
or work with a printer who will include in his price some time to go through your files and correct any pre-press problems before the job goes to press.
If you get several printing quotations, do not assume that the lowest bidder will necessarily deliver as good a print job as the high bidder or that because someone who is more expensive will deliver a better quality job. Be sure to look at samples of a printer's work, especially projects that are similar in size and complexity as your project. Make sure your printing quotes are really an apple to apple comparison.
Working With Printers
If you get several printing quotations, do not assume that the lowest bidder will necessarily deliver as good a print job as the high bidder or that because someone who is more expensive will deliver a better quality job. Be sure to look at samples of a printer's work, especially projects that are similar in size and complexity as your project. Make sure your printing quotes are really an apple to apple comparison.
Working With Printers
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
If you do not like creating printing specifications and working with printers, consider using a graphic designer as your go-between. If you are working with someone to design your projects already, they may have several printers they like to work with and your designer can handle the technical issues and work with the printer on your behalf.
If you are working with a new printer, be sure to get a number of samples of their work (and samples similar to the project you are having quoted). If you are on a tight deadline or the project is very complex, be sure to get some references from t
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
he printer; ask about the printer's ability to deliver as promised and how they deal with potential problems.
All printers are not created equal because printers vary in terms of press sizes and what is considered their ideal printing project. A printer with a smaller press might be more economical, but might have greater press limitations and could deliver a less than first-rate job. Make sure that the printer you select has the equipment and expertise to handle your project.
Before your project is printed, be sure to look at digital or matchprint proofs to make sure you are happy with the
All printers are not created equal because printers vary in terms of press sizes and what is considered their ideal printing project. A printer with a smaller press might be more economical, but might have greater press limitations and could deliver a less than first-rate job. Make sure that the printer you select has the equipment and expertise to handle your project.
Before your project is printed, be sure to look at digital or matchprint proofs to make sure you are happy with the
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
quality of the proof. Many printers will allow you to critically examine the first color proofs and make color adjustments, providing you with a second set of color proofs prior to printing. Keep in mind that making color corrections will send your job back through pre-press and may delay the printing schedule significantly.
Press Proofing Press proofing is one way to make sure you have no surprises after your project is printed. Usually press proofing is done by the client, the project's designer or the printing sales representative handling the job. Keep in mind that some printers
Press Proofing Press proofing is one way to make sure you have no surprises after your project is printed. Usually press proofing is done by the client, the project's designer or the printing sales representative handling the job. Keep in mind that some printers
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
may charge extra to press proof as it means holding up the press run until the press proof is complete. Press hold-ups can be costly, especially if the press proof requires sending the job back to pre-press.
Press proofing is probably more important with long press-runs where you are printing tens of thousands of a brochure or other marketing materials. If you have a small print run of a few thousand, the time and effort required to press proof may not be worth it.
During a press proof, you should look for color fidelity by comparing the printed sheet against the matchprint or digital proof
Press proofing is probably more important with long press-runs where you are printing tens of thousands of a brochure or other marketing materials. If you have a small print run of a few thousand, the time and effort required to press proof may not be worth it.
During a press proof, you should look for color fidelity by comparing the printed sheet against the matchprint or digital proof
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
. You also will want to look at solid areas making sure there are no dust spots creating white specks. Be sure to inspect small type or type that is created using screens or reversed out of a color background.
Generally, minor color adjustments can be made to enhance or create final color balance in a four-color piece, however, extensive color adjustments on-press is not the way to correct poor quality pre-press work. When correcting on the press you are "tweaking", and you will just not have the controls over individual images used within your print job as you do when the job is still in pr
Generally, minor color adjustments can be made to enhance or create final color balance in a four-color piece, however, extensive color adjustments on-press is not the way to correct poor quality pre-press work. When correcting on the press you are "tweaking", and you will just not have the controls over individual images used within your print job as you do when the job is still in pr
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
e-press.
While slight color adjustments on-press is perfectly acceptable, keep in mind that any color adjustments will affect the length of the sheet; that is, anything ahead of or behind the area affected by color adjustments on press will be affected as it passes through the press.
Saving Money With Out of Town Printers
While it is tempting to use printing companies who advertise through the Internet and offer great pricing on four-color printing, keep in mind that many of these printers "gang" print, that is, they put your printing job on a large press sheet along with many other
While slight color adjustments on-press is perfectly acceptable, keep in mind that any color adjustments will affect the length of the sheet; that is, anything ahead of or behind the area affected by color adjustments on press will be affected as it passes through the press.
Saving Money With Out of Town Printers
While it is tempting to use printing companies who advertise through the Internet and offer great pricing on four-color printing, keep in mind that many of these printers "gang" print, that is, they put your printing job on a large press sheet along with many other
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
customers, so it may not be possible for your job to get the individual attention it needs. Press proofing may be difficult or impossible due to the location of the printer or printing schedule (as some printers have three shifts).
Always get print samples before you use an out of town printer and make sure you understand their policies on packaging and shipping, and problems after the printing is done, so you do not save money on one hand, only to lose money through "gotchas" your local printer might not have.
When I am working with a printer for the first time, I always give the printer
Always get print samples before you use an out of town printer and make sure you understand their policies on packaging and shipping, and problems after the printing is done, so you do not save money on one hand, only to lose money through "gotchas" your local printer might not have.
When I am working with a printer for the first time, I always give the printer
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
a small project to see how it is to work with them. Keep in mind that you are not just paying for putting the ink on the paper with printing. You are paying for expertise, customer service, reliability knowing that your printer will work with you to resolve any problems or issues before your job is printed.
Do not rely on .PDF proofs when working with any printer. Insist on getting a digital proof or a matchprint proof so you have a good representation of what you will be getting once the job is printed. A .PDF proof sent by e-mail is fine for checking after changes may have been made, and u
Do not rely on .PDF proofs when working with any printer. Insist on getting a digital proof or a matchprint proof so you have a good representation of what you will be getting once the job is printed. A .PDF proof sent by e-mail is fine for checking after changes may have been made, and u
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
nless your monitor is calibrated precisely, the colors you see in a .PDF or your own printed proof will usually be very different from what the actual printing will be.
Is Four Color Printing Worth The Price? The answer is yes for some companies and some situations, and no for others.
The bottom line is to consider carefully the reasons to use four-color process in the first place, and to take care when completing all pre-press work. Knowing your printer or your printer's capabilities ahead of time will make for less stress and you will know what to expect if something does go wrong
Is Four Color Printing Worth The Price? The answer is yes for some companies and some situations, and no for others.
The bottom line is to consider carefully the reasons to use four-color process in the first place, and to take care when completing all pre-press work. Knowing your printer or your printer's capabilities ahead of time will make for less stress and you will know what to expect if something does go wrong
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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