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The following anti spam programs are effective, popular and (the best part) free!

eXpurgate

Expurgate is an effective, if unusual, anti spam program.

Here's what that means:

You have to use at leas

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t two different email accounts to use eXpurgate. Your existing email address has to be set up to forward your incoming mail to eXpurgate where the messages get filtered. After that, the mail is sent to anothe

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r account for distribution to you.

Beyond that, eXpurgate uses familiar anti spam techniques such as

Pros

* eXpurgate is easy to set up and maintain.

* Unlike a Bayesian filter, this anti spam program

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

requires no training to reach optimum efficiency.

* Saves you download time and resources

Cons

* EXpurgate does not "get" your mail from a POP or IMAP account -- you have to set up your email box to f

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

orward it.

* After filtering your mail, eXpurgate sends the mail to a second account of your choosing -- and/but this address MUST NOT get into the hands of spammers...or else you are back where you star

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ted.

* EXpurgate's spam filter rate isn't as good as an anti spam program that uses a fully trained Bayesian filter

G-Lock SpamCombat

SpamCombat combines the personal approach of Bayesian filter

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ing with the "two-heads-are-better-than-one" approach of DNS blacklists to capture spam very effecetively. It also uses content analysis to uncover bogus HTML that may be hiding real spam. All of these featur

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s eliminate a lot of spam at the server before you download it to your computer.

The downside to SpamCombat is that it only works for POP email accounts. Not only that: it cannot work as proxy, so you are re

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

quired to check your email twice -- first in SpamCombat, then in your email client.

SpamCombat makes the process of training the Bayesian filter a bit difficult by presenting you with an interface that is ki

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nd of cluttered-looking.

SpamCombat supports white- and blacklists through regular expressions -- not exactly my favorite thing to do as it is kind of involved. Luckily, this isn't a core function of SpamCom

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

bat and it works fine without it.

Pros

* Uses multiple blocking and filtering techniques for high success rate

* Uses Bayesian filtering

* DNS blacklists

* Can detect bogus HTML that hide

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s spam messaging

Cons

* Supports POP accounts only,

* Cannot work as a proxy

* The interface is cluttered

* Message preview feature not the greatestnot ideal

K9

K9 uses a Bayesia

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n filter to find spam. As you know, you will have to tell K9 what you consider to be spam and what you consider to be good email. K9 will do the rest and put the spam in any folder you want. You can periodica

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lly check the folder to make sure K9 is not junking any real mail; if that is the case, you can correct K9's filter easily so it won't happen again.

K9 can also connect to a DNS blacklist for known spammers,

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

although some users suggest that this won't increase K9's accuracy.

K9 works as a POP proxy so it works with just about any email software. The downside to this is that it only works with POP accounts.

Pros

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

* Works with any email client

Cons

* No remote administration

* No web interface

* Only supports POP accounts

MailWasher

Mailwasher deletes spam right at the server through a sy

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

stem of filters that use regular expressions (formulas that describe a series of words or phrases). It also uses black- and whitelists, relying on the information in the email header (sender, subject info, et

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

c.). This makes MailWasher easy to use and maintain.

MailWasher lacks the kinds of scoring filters or Bayesian statistics that automatically adjust to spammers' tactics. Another drawback is that it you can o

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nly use Mailwashwer on one POP account. Not only that: it doesn't work with IMAP accounts. It also doesn't work with Web-based email accounts.

Pros

* Mostly easy to maintain and use

* Uses black- a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nd whitelists of senders

Cons

* Supports only one POP account

* Doesn't use scoring filters or statistical analysis which requires you to perform some amount of maintenance

(End of Part One of Two

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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