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So you think all of your subscribers are receiving your ezine? Better think again. With the rise of Spam filtering software, both by ISP's and end users, odds are your ezine may be getting deleted before it's even delivered to your subscribers.

There are two main types of filters: tho

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

se installed on the end user's computer and server side programs used by Internet Service Providers. The most popular program used is http://SpamAssassin.org

So what does this mean to you as a publisher? If you want to make sure your ezine is being read you'll want to pay close atten

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ion to the tips given here. After all, do you spend your time writing a good ezine just to have it sent to the trash? I didn't think so.

Spam filters work by counting the words in your ezine that fall on their "target lists," each of which has been assigned a numeric value. After

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

they're done "scanning" your email, they add up your score. If your total value is above a set number, it is determined to be "spam" and sent to the trash bin. Gone forever, and your subscribers are none the wiser. Filters search the message, the header, the subject line and looks at

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the formatting as well. To see what Spam Assassin looks at go to.... http://www.spamassassin.org/tests.html

I personally use filtering software due to the hundreds of unsolicited messages I receive daily. But I always go through the "trash bin" first and glance through it before hi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tting the delete key to make sure it hasn't captured something I want or need. The problem is that most users of filtering software either don't want to spend the time, or don't know how to check it to see what was "killed." So many of them may be missing your ezine, even though the

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

have subscribed to receive it.

Now do you see how tough it is just getting your ezine into the hands of your subscribers? The trick is to be "smarter" then the filters and utilize some of the great free tools that have sprung up to help publishers with this exact problem.

Before se

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nding out your next issue, run it through one of these free checkers to see if it will make it past the filters and find out what your ezines total score is along with tips on how to improve.

1) SiteSell Spam Check http://spamcheck.sitesell.com

Go to the above url or submit your ezine

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

to mailto:spamcheck@sitesell.net with the word TEST in all caps before your ezine name in the subject line.

Example: TEST Merle's Mission Ezine

2) Lyris Content Checker http://www.lyris.com/contentchecker/

Runs your ezine through a battery of tests used by "Spam Assassin." Paste yo

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ur ezine into the web based form, hit submit and the results will be emailed to you.

3) AssuranceSys.com- If you don't mind parting with some of your cash, Assurance Systems will run a variety of tests for you and let you know how your ezine stacks up against the filters and if you'v

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

been blacklisted. Check them out at http://AssuranceSys.com

So what's considered "bad" to filtering software and what can you do to reduce your score? I thought you'd never ask. Here are some tips to help:

1) Be careful with your subject line- Avoid the word free or using all caps or

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

excessive punctuation.

2) Using a lot of fancy HTML formatting can hurt you. Many filters will kill HTML emails as a given mistaking them for viruses.

3) A larger size can actually help you. Anywhere from 20k to 40K is good and will actually subtract bad points from your total score

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

4) Blocking: Make sure your IP address is not being blacklisted. This can happen if your site is hosted on an open relay or you're sharing an IP address with someone who is a known spammer. You don't want to get yourself blacklisted so be careful here.

5) Avoid the use of the words

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

free, click here, remove, spam, and any others known to be on the list. This is pretty hard. Some publishers have resorted to putting * or ^ in exchange for letters. For example fr^e or Sp*m- It's highly debatable if this will work or not since most filters will be catching on to thi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

technique soon if they haven't already.

6) Set up free accounts at Yahoo and Hotmail and subscribe to your own ezine and monitor the boxes to see if your ezine is making it through their filters.

For further tips I recommend the following resources:

"Avoid the Spam Filter Trap" htt

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

p://assurance.sys.com/f/avoid-spam-filter-trap.pdf

"List of Filtering Trigger Words" http://www.iprofitsystems.com/articles/spamfilters.html

"20 Ways Opt in Emailers can Outsmart Spam Filters" http://www.wilsonweb.com/wmt8/spamfilter-avoidance.htm

Nice list of trigger words here: http

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

//www.sv-cs.spam.html

As you can see, publishing an ezine and getting it to your subscribers is no longer an easy task. One practice that has been adopted by some publishers is to send a follow-up email after your ezine has gone out, stating that it has been sent, including a url wher

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e your subscribers can go to read the issue online. I do this and every week that link registers 50 to 100 clicks, so obviously a lot of people aren't getting it the first time.

There's also a new service called Habeas.com which is a whitelisting tool. For a large sum of cash they'll

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

give you a line of code to add to your email headers which guarantees your message will pass through the filters. They have special relationships with ISP's and mail filters that recognize the header labeling you a "good guy." It's not inexpensive. Visit their site for more info on ho

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

w it works at http://habeas.com

There's no way to beat filtering, but by being informed and knowing what you're up against and how to improve, you'll stand a much better chance of getting your ezine where it needs to be. And that's why you started publishing in the 1st place, isn't it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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In my Ten Ways self-help manual, I referred to a definition of luck given by someone as: “when preparation meets opportunity”. Well, that was just one of the many definitions of luck that have been given by people who have achieved success (see more below). Some people always try to explain away another person’s success (or lack of it) as being due to luck (or bad luck). But the fact remains very obvious to anyone who will take an objective look at the issue. There is NO shortcut. Lasting success, very frequently, comes to those who apply themselves with commitment to a chosen cause.

Making money online is not so easy if you just run aimlessly and grab the things that you never wanted to piling up the garbage you never wanted to. Be smart and even better act smart. Grab some better opportunities and implement them.

Even some of the most experienced Internet marketers scratch their heads trying to figure out how they can make any money when somebody tells them to give their resale rights package for free. Where does the money come in if I'm just giving the stuff away? Well, if you're scratching your head as well, the following answers may come as a surprise to you, though when you think about them, they are quite obvious.

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