Just Other Articles - Internet and Businesses Online

In 1998, nearly 10% of all email traffic on the internet was SPAM. By 2003 that number had climbed to 50%, and the problem had gotten so bad tha

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t Congress passed the CAN-SPAM Act of 2003 (Controlling the Assault of Non-Solicited Pornography and Marketing Act)

The specific requirements a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nd penalties of that law, (which took effect in 2004) have done little to stem the tide of junk email we all receive. Today, in 2005, the percen

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tage of unsolicited email is at an all time high of 87% (source – Wired Magazine July 2005)

How can we even stand to check our email? Well I ca

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

n’t. That’s why I pay for a service to protect my entire domain name from all Spam. That’s a great solution for me, but it’s too expensive for a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

home or very small business user. How then can you protect yourself?

First, there are filtering options in Outlook and Outlook Express, and I

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

encourage you to investigate them further. More details on this are in my article from May of 2000 called “Managing your E-mail II” here http://

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

pdxtc.com/200005-managingemail2.htm

After trying about 6 other programs, I found a free version of some software that I used for a long time ca

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

lled Mailwasher. This program was easily trained and configured to learn all of my preferences, and for free, there’s nothing better. However, y

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ou I still basically have to check mail twice, once in a clunky web-interface to sift through all the blocked SPAM. I prefer to just check my ma

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

l normally, not worrying about a missed message.

In 2003, a friend recommended a service called Knowspam. That was a great solution that blocke

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

d 100% of all SPAM through a “permission based” system. A permission based system means that all new senders not on your list, will get a “veri

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

fication” email, asking them “Are you human?” Well, if they are really human, then they take the simple instructed action, and you’ll get their

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

email, as well as all future mail from them, unless you choose to block them later.

Many readers of my column tried Knowspam, and I got dozens

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

of positive comments. That wasn’t enough for Knowspam though, because they still went out of business.

Well the good news is that there’s a re

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

lacement for Knowspam. It’s called Spam Arrest, and it’s under $3 a month. It does everything that Knowspam used to do, and then some. I’ve now

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

set myself up with an affiliate account and arranged for you try it for free for 30 days.

First, you easily upload all of your contacts, and th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

en follow their easy directions to change your system mail settings, and anyone on your list or anyone you ever send mail to is automatically ap

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

proved.

The great news is that this works for up to 5 email accounts, and even works for AOL mail! If you want to see 100% of your spam get bl

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ocked, and not be embarrassed to let your kids see your inbox, then visit http://www.pdxtc.com/spamarrest and sign up for your free 30 day trial

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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