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Technicians at ActivSoftware recently analyzed over two hundred thousand tokens, also referred to

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

as words, in a bayesian spam filter on one of their busier local email servers. They analyzed do

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ens of items within the data. The most compelling was the spam to ham ratios. Ham is defined as l

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

egitimate email sent by legitimate email senders. The compiled list of over 50 words with the hig

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

est spam to ham ratio was the result.

Words like 'click' and 'here' don't show up as high, since

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

they are used so often in legitimate email. The ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

om">ActivSoftware list also reveals that words like 'madam' which is rarely found in legitima

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

te email, while readily found in spam email, had very high ratios. Using this method the team pro

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

uced a superior list of words found in spam email ordered not just by frequency of usage in spam,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

but offset by the frequency of usage in legitimate emails. The words are ordered from highest to

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

lowest Spam to Ham ratio.

This study empowered the coders and business employees at ActivSoftwar

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e with an increased ability to continue to track and, according to the team at ActivSoftware, eli

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

inate the negative impacts of spam on the business community. The team at ActivSoftware continues

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to attempt to learn spammers in order to increase the effectiveness and deliverability for custo

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ers using XM Mail Server.

Here's the top ten:

homeowner
discreet
m

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

adam

materially

unclaimed

anticipates

soma

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

preapproved

unconditionally

beneficiary

Note: This list has bee

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

n updated and might change frequently as we continue to hone it in. The newer version, 8/8/05, al

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

o includes bid information from Overture as well as the Spam:Ham ratios.

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

http://blog.activsoftware.com/entry/36/top_50_spam_words">See the newest spam to ham word list

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

Can you quickly separate between your qualified business prospects from your other prospects and suspects? If not, you may find this article of interest.

Have you been considering writing a book and just cannot seem to find the time? Well you might be surprised that you will have all the time in the world

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