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Like everybody who will ever read this, I get spam in my e-mail. Mine seems to fall into one of three categories. The first is the Nigerian scam about helping some poor, pathetic soul collect megabucks, supposedly from someone who

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

has died and left a fortune. I’m not sure what is worse: that there are people desperate enough to believe those messages, or that there are people despicable enough to prey on the desperate. The net result is the despicable con the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

desperate into sending money which the desperate will never see again.

The second type comes from people who sound innocent enough. They have a product or a business or a service or something else that is perfectly legitimate. The

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

surf the web, find one of my sites, find the “contact us” link, and send me information about whatever they have to offer. I suppose, in their minds, it isn’t any different than walking down the street or going through the telephon

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

book writing down addresses, and then sending out bulk business mail with the same offer. They could get the same information for more money and less time by buying a mailing list. THAT is perfectly legitimate. Harvesting e-mail

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ddresses off of web sites is NOT. Spam is officially defined as “unsolicited commercial electronic mail.” The key word is “unsolicited.” If I didn’t ask for it and you send it anyway, it is unsolicited. When people harvest e-mail

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

addresses off of web sites and then send commercial messages, that, by definition, is spam. I report them to my ISP and you should, too.

The third type isn’t so innocent. These people, like the second type of people already discu

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

sed, surf the web, find sites, and harvest the e-mail addresses from the “contact us” link. Instead of starting out by sending you what they have to offer, they get devious, sneaky, and just plain under-handed. They send you a mess

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ge asking for more information about whatever you have to offer on your site. When you graciously respond, it turns out they couldn’t care less about what you have to offer. The ONLY thing they want is to confirm your e-mail addres

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

so they can start to dump offers on you, hoping you will buy something from them. Nasty trick.

Let me give you an example from one that once came across my screen. It seemed to be from a nice lady with homey graphics and nice col

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

rs in her e-mail. If my memory serves me well, she even stated that she was disabled and looking for ways to earn a living off the internet. In my mind, that’s a hard combination to resist. A great deal of effort was put into this

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

to make it sound as if she had built an internet community around her site and services. Maybe she did; I don’t know. Anyway, I was na?ve enough to respond with the information she had requested. Soon solicitations for this, that,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nd whatever business offer, etc. began arriving in my inbox. I finally put two and two together and realized that they were from her, but I was still reluctant to report it as spam, so her messages went quietly into the trash. I me

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

n, she seemed SO NICE! Then I got this huffy message, apparently broadcast to her entire mailing list, about how if people didn’t want to receive her messages, why didn’t they just unsubscribe, etc. It seems quite a few people had

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

eported her as a spammer and she was getting into trouble. It was time for me to respond, so I told her, bluntly, that what she was sending out WAS spam. It was unsolicited. I never signed up to be on her mailing list, and no doub

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

the people who had reported her never signed up to be on her mailing list, either. I only responded to a request FROM HER for information and that in no way implied that I wanted to be on her mailing list or that I wanted to receiv

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e her offers. She must have gotten the message because I have received nothing else from her.

So how about you? Are guilty of sending out e-mail to people who did not specifically request to receive offers from you or about a busi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ess that you represent? If you go around looking for e-mail addresses to harvest for your own purposes, you are guilty of sending SPAM. Instead, post your offers on your web site and market them legitimately. It’s the right thing

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

o do. When people fill out your form, they are giving you permission to send them information. Keep a record so you can defend yourself if they ever forget what they did.

If you are on the receiving end of unsolicited offers, go a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ead and report them as spam. Don’t feel guilty; you are not the guilty party. Just make sure you really didn’t sign up for a newsletter or something and then forgot! It is sooooooooooooooo not cool to report spam that really isn’t

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Almost every report you pick up on Internet marketing and business success will deal with the mechanics of the business. For example, you'll learn how to find hungry niche markets. You'll learn how to create products that are in demand. You'll learn how to create a website and drive traffic to this website. You'll learn how to convert these visitors into buyers through good sales copy and via building relationships.

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