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A friend asked me: I don't get it. Why do spammers have such a hard time spelling things properly? I get mail trying to sell

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

me "viagggra", increase my "brest" size, or save me money accessing "pr0n" sites or buying "seks toys". Even more puzzling,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

there are plenty of spam messages where it takes me a few minutes to even figure out what the subject actually is, with subjec

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s like "sa vem oneyo n vviiiaaagra" or similar. What's the story? Why can't these people use a spell checking program??
I

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

have often wondered this myself, with spam messages like "YOU JUST WONT A GREENCARD" (don't they mean "won"?), "Morgage ref i

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

last opportunity" (don't they mean "mortgage")? and, my favorite "earn a college degre instantly" (they presumably mean "de

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

gree", but if they can't spell the word degree, how can I have confidence in the legitimacy of what they're offering??)
Bu

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

anyone who has spent more than about five minutes looking at the problem and attempted solutions to spam knows why there are

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

such rampant misspellings: to try and sidestep spam filters. In additional to individual spam filtering systems, there are n

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

w many Internet Service Providers who filter your email before it even gets to your mailbox, weeding out the most idiotic and

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

easily recognized of this junk.
Of course, if you are a physician and have patients who are concerned about that Merck Vio

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

xx prescription you wrote for them two years ago, it is theoretically possible that their message won't make it to you. If you

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

re a mortgage broker, well, news of your competitors offerings might be something you do want to receive. But overall

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

, most people don't want this junk, so the people clogging up the Internet with the billions of spam messages sent daily conti

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ue to try and sidestep these filtering mechanisms, and the misspellings, typos, and oddly presented words (like "0ffer" with

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a leading zero rather than "offer" with a letter o) presumably offer some minimal ability to do just that.
The irony of a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

l this, in my opinion, is that the more spammers try to do overt and stupid tricks to try and sidestep the filters, the less e

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ffective their messages are. They might measure 1 sale in 250,000 messages a success, but better targeting, legitimate offer

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

, well-written ad copy and genuine opt-in distribution lists might just improve those odds quite a bit. And if you're selling

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

something, wouldn't you like to avoid having 95% of the Internet spontaneously hate you because of your marketing techniques

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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If you are in the boat cleaning and washing business then you need to learn how to do sales so that you can deal with the customers. There are several types of customers and they have different needs. You will learn this overtime, but you will learn a lot quicker if you will listen more and do less selling or telling or talking.

If you've hung around in the search engine optimization industry (a.k.a. SEO industry) very long, you've probably heard the debate on ethical SEO tactics. Or, as it is often put, white hat tactics versus black hat tactics.

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