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Although there still seem to be some differences among the US Government, the lawmakers, the anti-spam organizations and the spammers regarding what is spam and what is not, identifying it is actually pretty easy: if you did not ask for it, you did not sign up on a mailing list related to it, and did not leave your e-mail address on a web f

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

orm asking for more information on it…it's spam! The spam issue is not about content, but solely about delivery method. The content of spam is and has always been irrelevant.

Again, if it is sent unsolicited and in bulk, it is spam plain and simple. Sure we want spam to stop. Nobody wants their e-mail address cycling around from spammer

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

o spammer. We can delete it, but have you ever stopped to consider how much time we actually spend each day hitting the ‘Delete’ button? We should not have to beg to be removed from something we did not ask to be put on in the first place! So where do we draw the line? When do we start thinking it is not worth logging into our email account

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

to read our messages? Despite the effort of thousands of angry spam victims pushing for stronger laws against spammers over the last few years, not much progress has been done in this respect. Moreover, in January 2004 the U.S. Government has passed the CAN-SPAM Act, a law backed overwhelmingly by spammers and large corporations, because it

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

legalized spamming instead of banning it. With the passage of CAN-SPAM, spamming has become legal throughout the United States. Now 23 million U.S. businesses can all begin spamming email addresses as long as they give users a way to opt-out. What CAN-SPAM makes illegal is the use of open proxies or any form of resource misappropriation as

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ell as use of false headers, which for the top spammers to avoid is business as usual.

We will not argue here about the motives of the US law makers to pass the CAN-SPAM, but rather focus on the problem of doing something about the spam in your mailbox. By doing more than "just hitting delete", you are helping to solve the problem. We shou

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d all exercise our right of control, or we will lose it.

The million dollar question is whether it is possible to stop spam. The most honest answer to this question is probably not -- but you can significantly reduce it. Below are some clear and simple tips to greatly reduce the amount of spam you get:

1) Use a separate email address when

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

you post messages to public forums, such as newsgroups and mailing lists. Never use your personal email address for this purpose -- or it will end up flooded with spam.

2) Consider acquiring multiple email addresses for different purposes. This helps to identify different sources and senders, and allows you to filter more effectively. For

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

nstance, you may have one for personal use only by friends, family or colleagues that is never used to request information or to subscribe to newsletters, discussion lists, etc. Another might be used just for sales inquiries or orders, or for making online purchases.

3) You can subscribe to services online that provide you with disposable

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ddresses that can be deleted if they begin to attract spam messages. This works because the disposable email addresses actually forward to a real email address of yours. The software lets you track which addresses are getting spam, and you can just resubscribe using a new, spam-free address. One company that offers disposable email accounts

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

is Sneakemail.

4) Remove your email address from your website. If you list or link to your email address, you can expect to be spammed. Thus, remove them wherever possible and use web-based forms instead. This will drastically cut down the amount of spam you receive if you have a website.

5) NEVER buy anything from a company that spams. D

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

o not visit their sites or ask for more information from a spam email that you have received. Over 95% of spam offers are scams! In fact, not responding to spam is the single most effective way to not get scammed on the Internet.

6) Filter your email. Using filters is key to managing your email effectively.

7) Consider subscribing to a sp

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

m prevention service. Make sure that any software or system you select gives you control of which email you get and does not automatically erase messages. Also, safeguard your newsletter and discussion list subscriptions. If you, your ISP or web host use spam filters or white lists, be sure to let them know that you want to receive messages

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

from any newsletters or discussion lists that you subscribe to.

8) Report the spam to agencies that maintain statistics. Such agencies generally compile statistics that may be useful in setting policy. One trusted anti-spam organization where you can report spammers is the Anti-SPAM League. Learn how to become a member for free by clicking

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

here.

9) Report fraudulent or otherwise illegal content to appropriate authorities. While fraud per se is an issue separate from spam, unsolicited email often contains offers for illegal or fraudulent products.

10) Contact your Internet Service Provider. Although this is unlikely to affect the amount of spam you receive since it is not th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ir fault that their system was attacked from outside, ISPs want to know about spam attacks, either to learn how to protect their system, or to set policy.

11) Contact the sender's Internet Service Provider(s). Most ISPs in the world forbid their members to send spam. Therefore, if your complaint is valid, then there is a good chance the sp

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

mmer will lose connectivity.

12) Demand restitution from the spammer. If you continually receive spam from a single source, you have a right to demand repayment for the time and resources the spammer used.

13) Initiate legal action against the spammer. This should be a last resort, as legal action is troublesome and expensive. However, we

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

l-executed legal action may do more than just get one spammer off your back: it may lower the amount of spam on the Internet in general. By forcing unsolicited and objectionable materials into our mailboxes, spam impairs our ability to communicate freely and costs Internet users billions of dollars annually. You do not have to put up with

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

it: your best recourse is to protest to those who dump their trash on your disk drives!

Organizations such as The Anti SPAM League give you the chance to report spamming companies and individuals and access valuable information on how to control the spam problem. The Anti SPAM League serves as a resource to identify companies on the intern

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

t that are safe to do business with. Also, to target which companies are trying to capture your personal information for the use of unsolicited mass marketing. Take a step forward in the battle against spam. Learn how to become a member for free by visiting www.Anti-Spam-League.org

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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In these times of tough competition among the retailers, if they indulge in price wars, it tends to reduce their profitability. It has been observed that customers give more importance to product quality and customer service than to price. Many companies have been able to sustain themselves in spite of charging a higher price for their product than their competitors with the help of better customer service. Steps such as mystery shopping, due diligence and visual merchandising can go a long way in developing trust and confidence in the minds of the customers and ensure their long-term support.

Would you like to have more energy and synergy in your job and career? If you are not enjoying work the way you used to and if you would like to contribute in a manner that produces more results with less effort, then energizing synergy is what you need to cultivate. This article gives you seven simple tips to increase your personal energy to help you make a synergistic impact at work.

More than ever before, 2007 will demand of most companies the ability to achieve measurable results that are specific to profitability, growth, cost containment and operational effectiveness. Of course, none of this will be possible without leadership and organizational change. This challenge will become a common theme in 2007 that will go uncompromised by the potential market gymnastics that we are likely to face. Without a doubt, success in 2007 will be directly dependent upon both individual and team performance. More importantly however, is the driving force that creates both individual and team effectiveness. That driving force is leadership at every level in the organization.

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