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Surfers go online mainly to find information. If you can satisfy that need then you will increase your traffic, enhance your brand, and acquire and retain more customers.

The catch is that your content-whether free on your site, distributed elsewhere gratis, or sold as an informational product-has to be killer content that's valuable in the eyes of consumers.

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

Entrepreneur.com's Tim Knox [2004] says information is the best product to sell online for the following reasons:

It's fast to create, fast to market.
There's no inventory to stock.
The start-up costs are low.
There's an automated sales and delivery process.
Customers get immediate access or delivery.

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

li>There are no shipping and handling charges.

Not every online business is looking toward creating and distributing information products as a revenue stream, however. Many webmasters are more interested in using the strategy to enhance their brand with visitors and with their peers. Top-notch content is also extremely effective as a marketing too

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

l to generate traffic for your site.

The branding and marketing applications are actually complementary: "Articles establish you as an expert in the marketplace, build inbound links to your sites, pre-sell your products, and help you rank higher in the search engines for your targeted keywords." [Crawford 2006] Recently, Beckart [2005] summarized the seven ke

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

benefits of writing articles and publishing them online:

Resource box. The short paragraph about the author included at the bottom of the published article is an opportunity to brand yourself, your business, and your website.
Inbound links. Every time your article is published there should be a live link to your website in the resource bo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

x. Include important keywords in the link text for extra points with the search engines.

Building credibility. Articles help establish your expertise. It's easier to gain a prospective client's trust when you have this credibility. Prospects that trust you are more likely to make a purchase.

Receptive audience. People who receive the e-zine

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

s containing your articles are voluntarily pre-selected because they're interested in the particular topics you're writing about.

Exposure. When your article is sent out to a publisher's list, it's an excellent result of your efforts. Also, many publishers place current articles on their homepage, later archiving them.

Leverage. You have co

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tent that you can leverage when you write articles. Whatever you write can be used for multiple purposes. Search engines look favorably on new content.

Viral marketing. Allow e-zine publishers to include your articles in their free e-books, as long as your resource box is included. Since these are being given away, your ad multiplies.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e practical application is straightforward-you write (or have written for you) a useful and interesting article; make it available for use on other sites, newsletters, or e-zines either directly or through a resource site; then wait for the organic benefits to accrue.

Resource sites that you can submit your articles to are popular with Web publishers of all t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ypes because they're perennially hungry for new content-often desperate for it, in fact. Several of the best resources for submitting your articles (or finding some) include:

Ezine @rticles (www.ezinearticles.com). Their searchable database of 100,000+ original articles allows newsletter publishers hungry for fresh content to find articles that the

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

can use for inclusion within their next newsletter.

GoArticles (www.goarticles.com). An article search engine and directory, updated daily. One of the largest article databases makes great content available to publishers when they want it, not when someone decides to send it.

IdeaMarketers (www.ideamarketers.com). Writers can post their ar

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ticles for free to be featured on the site and stored in a searchable database. Publishers, webmasters and e-zine editors then visit and find new content.

Distributing free content like this is one of the most powerful linking and traffic-generation strategies available to you. According to Michael Klasno [2006] reciprocal link exchanges are dead:

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

"This practice does not indicate either site as being an authority and actually gives a slight edge to the lesser ranked site. This strategy has already become obsolete and very soon the search engines will change their algorithms and teach their spiders to take it into account."

But that leaves three-way non-reciprocal linking in which all three sites get a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

unique inbound link without having to link back in return. Seems complicated (and unlikely!) but how it actually works is very simple-you send your article (linking back to you) to another site, a third site will refer to that article and thus link to them, and finally, you may want to link to that third site to drive traffic to your article and thus back to

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ou. All three get a one-way inbound link.

But it should be said that the three-way link exchange, like some other link building strategies, is not as effective as it used to be: “Despite what many people think, three-way link exchanges can be easily identified by search engines and if there are a large number of these types of links are present, it can result

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

in a ranking drop or ban.” Nevertheless, this remains a viable strategy if not overdone. The secret to leveraging three-way links effectively remains, as always, the quality of the link and of the content.

Delivering relevant links from relevant content is the key. [Klasno 2006] and Walsh [2005] both recommend three-way linking: "The idea is simple: you give

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

other websites content to put on their sites in exchange for a link to your site. The beauty of distributing content for links is that the links generally generate more traffic than links on a resources page. Plus, your article will pre-sell readers on the value of your site."

Branding and generating traffic by distributing valuable content is a powerful str

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tegy that you should be using or leveraging more effectively. But the absolute key is in making sure that your content really is valuable and delivers value to the readers.

Sources

Loren Beckart. "Using Ezine Articles to Promote Your Business," Webcredible 09/05. http://www.webcredible.co.uk/user-friendly-resources/web-credibility/ezine.shtml.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

Willie Crawford. "Generating Self-Sustaining Website Traffic," Mainstream Webmasters 02/08/06. http://www.mainstreamwebmasters.com/article856.html.

Michael Klasno. "The Silver Bullet of Inbound Links," Mainstream Webmasters 01/26/06. http://www.mainstreamwebmasters.com/article837.html.

Tim Knox. "The Best Product to Sell Online," Entrep

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

reneur.com 08/23/04. http://www.entrepreneur.com/article/0,4621,316820,00.html.

Joel Walsh. "Getting One-way Inbound Links: The Five Major Strategies," Mainstream Webmasters 07/25/05. http://www.mainstreamwebmasters.com/article594.html.

“Weak Links in Link Popularity,” eBizTutors Blog 10/08/06. http://www.ebiztutors.com/index.php/?p=266

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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