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Until recently, if a company wanted to implement an intranet, they first had to install an internal n

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

etwork. Next they had to install a web server and set it up to host their internal documents. This cr

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ated an intranet, which is an internal network that uses web-based technology. The difference between

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

an intranet and a traditional company network is that everything on the intranet is accessed through

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

a web browser.

To secure access to the intranet, the company needs to install special software, set

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

up firewalls, and install a VPN server or switch. The equipment could be very expensive and most comp

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nies had to hire or train someone to maintain everything.

As a result, intranets were beyond the rea

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ch of smaller companies. However, all of that has changed. There are now a number of service provider

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

that offer hosted intranet solutions, which allows a company to outsource all the hardware, software

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

and maintenance for their intranet. These service providers are sometimes referred to as intranet a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

plication service providers (intranet asp).

Why Host Outside Your Company?

For smaller companies, c

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

st may be the determining factor. For larger companies, unless the necessary infrastructure already

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

exists, not having to purchase new equipment and train personnel may make it more cost efficient than

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

doing it themselves.

Advantages of a Hosted Intranet

• Hardware and software do not need to be purc

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

hased or installed

• Security measures such as authentication, regular backups and disaster recovery

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

are already in place

• Personnel to maintain the equipment do not need to be hired or trained

• Man

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

y applications are already available from the hosting company

• Technical support provided by the ho

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ting company

Disadvantages of a Hosted Intranet

• Data may or may not be more secure than if it was

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

all kept internal to your company

• Possible limitations on the software you use and services you c

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

n provide

• For larger companies, it may be more expensive over the long run than hosting internally

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Although its presence lingered unaddressed for many years, environmental noise is now recognized as a significant health issue. Environmental or ambient noise is unwanted or harmful outdoor sound created by human activities, including noise emitted by means of transport - road traffic, rail traffic, air traffic - and from sites of industrial activity. From delivery trucks to air conditioners, we are constantly bombarded by sounds that go unnoticed for the most part. However, out-of-earshot should not mean out-of-mind. It is precisely these innocuous environmental noises that should be sounding an alarm.

There is a huge misconception of Internet directories these days. People seem to think that the ONLY way to find information on the Internet is to use a search engine. This is a problem I would like to address in this article.

The Google Allegra update has changed search engine optimization techniques. Make sure your site keeps ranking well by following some simple rules.

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