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We all hear how easy it is for the rich and how effortless they seemed to have acquired their wealth. What most people don’t realise is

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

that there are certain principles and rules that guide the rich in contrast to the less fortunate of us.

The first and probably most p

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rominent characteristics of the rich, is how they handle themselves under pressure and setbacks.

First contributing factor of the rich

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

becoming wealthier is Persistence.
The number one factor why the rich keep their wealth from generation to generation. They lack th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e sense of failure and giving up, this makes them even stronger and even richer because they learn from their mistakes.

The second con

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tributing factor is Mental Capital.
Haven’t we all heard stories of the likes of Donald Trump going bankrupt and become indebted in

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

millions and millions of dollars only to resurface even stronger! How is this achieved I here you ask? Well the rich have a firm belie

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

f of “mental capital” being the real capital in their life. They don’t need physical capital to create money, their ideas and their tho

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ught processes is what accumulates money.

Next follows Time Management.
The rich are very focused on what they do, and how they sp

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

end their time. They recognize that time is one of the Most precious commodities they have, so they spend it wisely and effectively. Th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ey keep themselves informed and learn new skills to stay Competitive. This is in contrast to what a lot of people believe about the ric

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

h, where the common misconception is that they don’t really do anything except play golf, go shopping and travelling around the world.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

I would say they do all that, but it’s a very calculated process. They are in control of there time, not the other way around.

And las

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

tly Vocabulary.
The rich knows and understands that words are power and ultimately wealth. By having a rich vocabulary, they empowe

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

r themselves with words that attract wealth. Examples of this might be financial terms like compounding, present value, internal rates

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

of return etc. These words automatically put them in a higher standing with their stakeholders such as bank managers, investors etc. So

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

essentially they are buying themselves credibility and good standing by using complex financial terms. They also empower themselves wi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

th using positive words like success, vitality, vibrant, healthy, unstoppable etc. These words act like a cycle of success and by using

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

these words daily they establish a habitual pattern that I would call the “cycle of success”.

These are the core reasons I believe th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e rich get richer. And in most cases they communicate the same wisdom to their children and grandchildren in order to “preserve wealth”

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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