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As you would expect from a country which has so much influence around the world, the US leads the way in worldwide finance, bu

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t do you know how strong the UK financial Sector is? The mover and shakers? The big money earners?

While the UK finance secto

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r has seen many high profile big money takeovers, the leading banking groups have a massive presence on the high street and ab

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

road, and they are worth hundreds of billions between them.

While not all of their operations are UK based, many have chosen

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

he UK as their base, e.g. HSBC and Standard Chartered, which probably have the largest worldwide presence of all of the UK ban

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ks. Compare that with for example the Alliance & Leicester which is 100% UK based, and you start to get a feel for the wide v

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ariety of banking groups operating out of the UK.

While the major banks are often in the press for their big money profits, d

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

you really know the size and profitability of some of the UK’s best known financial conglomerates? You may find these figures

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

surprising :-

Name : HSBC

Value Of Group : ?105.57 billion

Profits in 2005 : ?15.081 billion

The business lines of HSBC c

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

over the world, although there is a large historical presence in the Far Eastern markets, due to the origins of the bank. The

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

UK exposure is predominately through Midland Bank which was acquired many years ago.

Click here for the up to date share pric

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e and financial information.

Name : Royal Bank of Scotland

Value Of Group : ?65.34 billion

Profits in 2005 : ?5.501 billion

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

While the Royal Bank of Scotland obviously has it roots in the Scottish financial sector, the company now have worldwide exp

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

osure - with the US one of their main markets. The company really took off after the acquisition of NatWest Bank which moved

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

he group into the higher league. Tight cost controls, and increased returns on investment have helped the group grow.

Click

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

here for the up to date share price and financial information.

Name : Barclays Bank

Value Of Group : ?48.72 billion

Profits

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

in 2005 : ?3.447 billion

Barclays has a history of difficulty controlling bad debts, and suffered particularly when third wo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ld bad debts rose in the 1980s and 1990s. While one of the oldest banking groups in the UK, the company have struggled to kee

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

p up with newer, fresher competitors and are seen by many as the next takeover target - with a number of US Groups said to be

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

monitoring their situation closely.

Click here for the up to date share price and financial information.

Part Two To Follow…

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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ISO 9000 is a set of standards internationally accepted by businesses and consumers. It allows organizations to establish and monitor quality management systems. ISO 9000 standards are considered to be generic standards since they can apply to any business, product or service irrespective of the industry. They have been developed and are maintained by the International Organization for Standardization (ISO).

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